Patents by Inventor Annarita Del Gatto

Annarita Del Gatto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective ??receptor peptide antagonist for therapeutic and diagnostic applications
    Patent number: 9309288
    Abstract: The present invention is related to new peptide antagonists of ?v?3 receptor, designed on the basis of the crystal structure of integrin ?v?3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the ?v?3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for ?v?3-targeted therapy and imaging.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: April 12, 2016
    Assignee: ADVANCED ACCELERATOR APPLICATIONS
    Inventors: Annarita Del Gatto, Laura Zaccaro, Carlo Pedone, Michele Saviano
  • SELECTIVE ALFAVBETA3 RECEPTOR PEPTIDE ANTAGONIST FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
    Publication number: 20140094412
    Abstract: The present invention is related to new peptide antagonists of ?v?3 receptor, designed on the basis of the crystal structure of integrin ?v?3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the ?v?3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for ?v?3-targeted therapy and imaging.
    Type: Application
    Filed: August 30, 2013
    Publication date: April 3, 2014
    Applicant: Advanced Accelerator Applications
    Inventors: Annarita DEL GATTO, Laura ZACCARO, Carlo PEDONE, Michele SAVIANO
  • Selective ?v?3 receptor peptide antagonist for therapeutic and diagnostic applications
    Patent number: 8546526
    Abstract: The present invention is related to new peptide antagonists of ?v?3 receptor, designed on the basis of the crystal structure of integrin ?v?3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the ?v?3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for ?v?3-targeted therapy and imaging.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: October 1, 2013
    Assignee: Advanced Accelerator Applications
    Inventors: Annarita del Gatto, Laura Zaccaro, Carlo Pedone, Michele Saviano
  • Selective Alfavbetas Receptor Peptide Antagonist for Therapeutic and Diagnostic Applications
    Publication number: 20080213190
    Abstract: The present invention is related to new peptide antagonists of ?v?3 receptor, designed on the basis of the crystal structure of integrin ?v?3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the ?v?3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for ?v?3-targeted therapy and imaging.
    Type: Application
    Filed: October 9, 2006
    Publication date: September 4, 2008
    Inventors: Annarita Del Gatto, Laura Zaccaro, Carlo Pedone, Michele Saviano