Patents by Inventor Anne Bourson

Anne Bourson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Octahydro phenanthridine derivatives useful as NMDA-R receptor subtype blockers
    Patent number: 6071929
    Abstract: The present invention relates to the use of tetrahydroisoquinoline derivatives of the general formula: ##STR1## wherein: A is arylR.sup.1 is hydrogen, hydroxy, lower alkyl, lower alkoxy, R--CO-- or R--COO--, wherein R is lower alkyl;R.sup.2 is hydrogen, lower alkyl or cycloalkylR.sup.3 -R.sup.7 are independently hydrogen, lower alkyl, lower alkoxy, hydroxy orR.sup.3 and R.sup.4 taken together are --(CH.sub.2).sub.n -- orR.sup.6 and R.sup.7 taken together are --OCH.sub.2 O-- andn is 3 or 4,as well as pharmaceutically acceptable salts for the manufacture of medicaments for the control or treatment of diseases which represent therapeutic indications for NMDA receptor subtype specific blockers.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: June 6, 2000
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alexander Alanine, Anne Bourson, Bernd Buttelmann, Gunther Fischer, Marie-Paule Heitz Neidhart, Vincent Mutel, Emmanuel Pinard, Stephan Rover, Gerhard Trube, Rene Wyler
  • Use of 4-phenyl-3,6-dihydro-2H-pyridyl derivatives
    Patent number: 5962472
    Abstract: The present invention relates to the use of compounds of general formula ##STR1## wherein R.sup.1 is hydrogen, halogen, lower alkyl or lower alkoxy;R.sup.2 is hydrogen;R.sup.3 is hydrogen, amino, ureido, lower alkylcarbonyl, lower alkyl-sulfonylamino, lower alkylcarbamoyl, carbamoyl, lower alkyloxycarbamoyl, lower alkylamino orR.sup.2 and R.sup.3 taken together are --(CH.sub.2).sub.m --X is methylene, hydroxymethylene, lower alkoxymethylene or carbonyl,n is 0, 1 or 2 andm is 3 or 4as well as pharmaceutically acceptable salts for the control or treatment of diseases which represent therapeutic indications for NMDA receptor subtype specific blockers.
    Type: Grant
    Filed: March 7, 1997
    Date of Patent: October 5, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Anne Bourson, Gunther Fischer, Marie-Paule Heitz Neidhart, Vincent Mutel, Gerhard Trube
  • Tetrahydroisoquinoline derivatives
    Patent number: 5952344
    Abstract: The present invention relates to the use of tetrahydroisoquinoline derivatives of the general formula ##STR1## wherein A is arylR.sup.1 is hydrogen, hydroxy, lower alkyl, lower alkoxy, R--CO-- or R--COO--, wherein R is lower alkyl;R.sup.2 is hydrogen, lower alkyl or cycloalkylR.sup.3 -R.sup.7 are independently hydrogen, lower alkyl, lower alkoxy, hydroxy orR.sup.3 and R.sup.4 taken together are --(CH.sub.2).sub.n -- orR.sup.6 and R.sup.7 taken together are --OCH.sub.2 O-- andn is 3 or 4,as well as pharmaceutically acceptable salts for the manufacture of medicaments for the control or treatment of diseases which represent therapeutic indications for NMDA receptor subtype specific blockers.
    Type: Grant
    Filed: January 19, 1998
    Date of Patent: September 14, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Alanine, Anne Bourson, Bernd Buttelmann, Gunther Fischer, Marie-Paule Heitz Neidhart, Vincent Mutel, Emmanuel Pinard, Stephan Rover, Gerhard Trube, Rene Wyler