Patents by Inventor Anne CARPENTER VAN DYK

Anne CARPENTER VAN DYK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for culturing epithelial cells
    Patent number: 11788063
    Abstract: The present invention features assays for co-culturing primary cells while maintaining key biological activities specific to the primary cells. The invention is based, at least in part, on the discovery that compositions and methods for primary cells in a high-throughput co-culture platform, image analysis for distinguishing cells in co-cultures and assays that are suitable for screening of agents in epithelial cells, such as hepatocytes.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: October 17, 2023
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Sangeeta Bhatia, Jing Shan, Anne Carpenter Van Dyk, David Logan, Nathan Ross
  • COMPOSITIONS AND METHODS FOR TREATING PROLIFERATIVE DISEASES
    Publication number: 20230255970
    Abstract: The present invention features compositions and methods for treating proliferative diseases such as cancer (e.g., sarcoma, pancreas, prostate, head and neck, liver, and breast cancer) that inhibit the growth of NF-?B and/or Hippo associated neoplasias.
    Type: Application
    Filed: August 12, 2021
    Publication date: August 17, 2023
    Applicants: The Broad Institute, Inc., The Trustees of the University of Pennsylvania
    Inventors: Tzipora Sarah Karin EISINGER, Gabrielle CIOTTI, Ashley M. FULLER, Mohammad ROHBAN, Anne Carpenter VAN DYK, Shantanu SINGH
  • SYSTEMS AND METHODS FOR CULTURING EPITHELIAL CELLS
    Publication number: 20210047617
    Abstract: The present invention features assays for co-culturing primary cells while maintaining key biological activities specific to the primary cells. The invention is based, at least in part, on the discovery that compositions and methods for primary cells in a high-throughput co-culture platform, image analysis for distinguishing cells in co-cultures and assays that are suitable for screening of agents in epithelial cells, such as hepatocytes.
    Type: Application
    Filed: August 27, 2020
    Publication date: February 18, 2021
    Applicant: The Broad Institute, Inc.
    Inventors: Sangeeta Bhatia, Jing Shan, Anne Carpenter Van Dyk, David Logan, Nathan Ross
  • Systems and methods for culturing epithelial cells
    Patent number: 10801015
    Abstract: The present invention features assays for co-culturing primary cells while maintaining key biological activities specific to the primary cells. The invention is based, at least in part, on the discovery that compositions and methods for primary cells in a high-throughput co-culture platform, image analysis for distinguishing cells in co-cultures and assays that are suitable for screening of agents in epithelial cells, such as hepatocytes.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 13, 2020
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Sangeeta Bhatia, Jing Shan, Anne Carpenter Van Dyk, David Logan, Nathan Ross
  • METHOD FOR LABEL-FREE IMAGE CYTOMETRY
    Publication number: 20170052106
    Abstract: A computer-implemented method for the label-free classification of cells using image cytometry is provided. In some exemplary embodiments of the computer implemented method, the classification is the classification of the cells, such as individual cells, into a phase of the cell cycle or by cell type. A user computing device receives as an input one or more images of a cell obtained from a image cytometer. The user computing device extracts features form the one or more images, such as brightfield and/or darkfield images. The user computing device classifies the cell in the one or more images based on the extracted features using a cell classifier. The user computing device then outputs the class label of the cell, as defined by the classifier.
    Type: Application
    Filed: April 27, 2015
    Publication date: February 23, 2017
    Applicants: The Broad Institute, Inc., Swansea University, Helmholtz Zentrum Munchen
    Inventors: Holger HENNIG, Paul REES, Thomas BLASI, Anne CARPENTER VAN DYK