Patents by Inventor Anne Corlu

Anne Corlu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INDUCING HUMAN CHOLANGIOCYTE DIFFERENTIATION
    Publication number: 20210324338
    Abstract: The invention relates to a method for inducing human cholangiocyte differentiation of progenitor cells called hepatoblasts. More specifically, the invention relates to a method for differentiating hepatoblasts to cholangiocytes by culturing said hepatoblasts with a particular medium having interleukin-6 (IL-6) activity. The differentiation method can specifically induce cholangiocyte dilferentiation from hepatoblasts, and the human cholangiocytes differentiated according to the invention may be useful for drug discovery for treatment of cholangiopathies and bioengineered livers.
    Type: Application
    Filed: May 20, 2021
    Publication date: October 21, 2021
    Inventors: Anne DUBART KUPPERSCHMITT, Anne WEBER BENAROUS, Anne CORLU, Noushin DIANAT
  • Method for inducing human cholangiocyte differentiation
    Patent number: 11066649
    Abstract: The invention relates to a method for inducing human cholangiocyte differentiation of progenitor cells called hepatoblasts. More specifically, the invention relates to a method for differentiating hepatoblasts to cholangiocytes by culturing said hepatoblasts with a particular medium having interleukin-6 (IL-6) activity. The differentiation method can specifically induce cholangiocyte differentiation from hepatoblasts, and the human cholangiocytes differentiated according to the invention may be useful for drug discovery for treatment of cholangiopathies and bioengineered livers.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: July 20, 2021
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ PARIS-SACLAY, UNIVERSITE DE RENNES
    Inventors: Anne Dubart Kupperschmitt, Anne Weber Benarous, Anne Corlu, Noushin Dianat
  • METHOD FOR INDUCING HUMAN CHOLANGIOCYTE DIFFERENTIATION
    Publication number: 20160376557
    Abstract: The invention relates to a method for inducing human cholangiocyte differentiation of progenitor cells called hepatoblasts. More specifically, the invention relates to a method for differentiating hepatoblasts to cholangiocytes by culturing said hepatoblasts with a particular medium having interleukin-6 (IL-6) activity. The differentiation method can specifically induce cholangiocyte differentiation from hepatoblasts, and the human cholangiocytes differentiated according to the invention may be useful for drug discovery for treatment of cholangiopathies and bioengineered livers.
    Type: Application
    Filed: March 19, 2015
    Publication date: December 29, 2016
    Inventors: Anne DUBART KUPPERSCHMITT, Anne WEBER BENAROUS, Anne CORLU, Noushin DIANAT
  • Methods for inducing active hepatocytes proliferation, kits using such methods and uses of said kits
    Publication number: 20050244959
    Abstract: A method for inducing hepatocyte proliferation in long term primary culture involves the steps of: (a) treating the culture with a cytokine and a growth factor; (b) terminating the treatment of step (a) to establish a quiescent phase; and (c) repeating steps (a) and (b) successively to induce several waves of proliferation.
    Type: Application
    Filed: March 30, 2005
    Publication date: November 3, 2005
    Inventors: Anne Corlu, Anne-Laure Serandour, Christiane Guguen-Guillouzo, Pascal Loyer
  • Factors for cellular functional regulation and biological applications thereof
    Patent number: 5859192
    Abstract: The invention relates to proteins characterized in that they are proteins for communication between cells of a given type and the contiguous or proximal heterologous cells.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: January 12, 1999
    Assignee: Cabinet Armengaud Aine
    Inventors: Christiane Guillouzo, Anne Corlu, Bernard Kneip