Patents by Inventor Anne Corrigan

Anne Corrigan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FSH-releasing peptides
    Patent number: 4973577
    Abstract: A 28,000-dalton protein with FSH-releasing activity is isolated from porcine follicular fluid in a multi-step procedure including gel filtration, ion exchange chromatography and several reverse-phase high-performance liquid chromatography steps. The 28 kD protein promotes secretion of FSH, but not of LH, in a rat anterior pituitary monolayer culture system, exhibiting an EC.sub.50 of 0.5 ng/ml. These peptides are dimers of inhibin .beta.-chains of mammals, and homodimers or heterodimers of the .beta..sub.A and .beta..sub.B chains are biologically active to regulate fertility of various mammalian species, including humans.
    Type: Grant
    Filed: August 31, 1987
    Date of Patent: November 27, 1990
    Assignee: The Salk Institute for Biological Studies
    Inventors: Wylie W. Vale, Jr., Jean E. F. Rivier, Richard A. McClintock, Anne Corrigan, Joan Vaughan, Joachim Spiess, Nicholas C. Ling, Shao-Yao Ying, Frederick S. Esch, Roger C. L. Guillemin