Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: A furniture item (102) convertible between a chair and a table. It has two panels (104, 106) hinged together and moveable between: —a chair configuration, in which one panel (104) provides a seat and the other panel (106) provides a backrest, and—a table configuration, in which the panels form a table top. A moveable support member (114) is rotatable between a stowed position beneath one panel (104) when in the chair configuration to a raised position in which the moveable support member (114) provides support to the underside of one panel (104) and support to the hinge (105).

Abstract: A furniture item (102) convertible between a chair and a table. It has two panels (104, 106) hinged together and moveable between: —a chair configuration, in which one panel (104) provides a seat and the other panel (106) provides a backrest, and—a table configuration, in which the panels form a table top. A moveable support member (114) is rotatable between a stowed position beneath one panel (104) when in the chair configuration to a raised position in which the moveable support member (114) provides support to the underside of one panel (104) and support to the hinge (105).

Abstract: The invention relates to a method of detecting the presence of mycoplasma in a test sample comprising: (i) providing a test sample; and (ii) detecting and/or measuring the activity of acetate kinase and/or carbamate kinase in the test sample, the activity being indicative of contamination by mycoplasma.

Abstract: The invention relates to a method of detecting the presence of mycoplasma in a test sample comprising: