Patents by Inventor Anne E. Goodbody

Anne E. Goodbody has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ovarian cancer ascites factor, in isolated form
    Patent number: 5326690
    Abstract: Herein described is an ovarian cancer activating factor that has been isolated from ovarian cancer ascites fluid. The factor may be utilized in its isolated form in a screening program aimed at identifying inhibitors of factor-mediated ovarian cancer activation, or as a growth supplement useful for culturing ovarian and other cancer cell lines.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: July 5, 1994
    Assignee: Allelix Biopharmaceuticals Inc.
    Inventors: Yan Xu, Anne E. Goodbody
  • Ovarian cancer ascites factor, in isolated form
    Patent number: 5277917
    Abstract: Herein described is an ovarian cancer activating factor that has been isolated from ovarian cancer ascites fluid. The factor may be utilized in its isolated form in a screening program aimed at identifying inhibitors of factor-mediated ovarian cancer activation, or as a growth supplement useful for culturing ovarian and other cancer cell lines.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: January 11, 1994
    Assignee: Allelix Biopharmaceuticals Inc.
    Inventors: Yan Xu, Anne E. Goodbody
  • Enzymatic preparation of 3',4'-anhydrovinblastine
    Patent number: 4918011
    Abstract: 3',4'-anhydrovinblastine, a precursor of the anti-tumor alkaloids vincristine and vinblastine, is prepared by the enzymatic coupling of catharanthine and vindoline using an iron-containing compound such as peroxidase optionally in the presence of a peroxide. Substantially enhanced yields are obtained.
    Type: Grant
    Filed: August 4, 1986
    Date of Patent: April 17, 1990
    Assignee: Allelix Biopharmaceuticals Inc.
    Inventors: Anne E. Goodbody, Endo Tsuyoshi, John Vukovic, Masanaru Misawa
  • Extraction of alkaloids of Catharanthus roseus tissue
    Patent number: 4831133
    Abstract: Alkaloids present in Catharanthus roseus tissue are selectively concentrated by aqueous extraction of ground tissue followed by extraction with organic solvent e.g. ethyl acetate. The resultant concentrate is rich in catharanthine, vindoline and 3',4'-anhydrovinblastine (AVLB). Yield of AVLB is enhanced by addition to the aqueous extraction medium of acid, salt, or hydrogen peroxide and can be further enhanced through the addition of sodium borohydride.
    Type: Grant
    Filed: May 1, 1987
    Date of Patent: May 16, 1989
    Assignee: Allelix, Inc.
    Inventors: Anne E. Goodbody, Colin D. Watson, Masanaru Misawa
  • Production of alkaloid dimers using ferric ion
    Patent number: 4778885
    Abstract: Alkaloid dimers are formed by coupling vindoline and catharanthine in the presence of ferric ion. The predominant products are 3',4'-anhydrovinblastine and vinblastine when reaction conditions are selected appropriately.
    Type: Grant
    Filed: September 18, 1986
    Date of Patent: October 18, 1988
    Assignee: Allelix Inc.
    Inventors: John Vukovic, Anne E. Goodbody