Patents by Inventor Anne-Frederique Le Clercq

Anne-Frederique Le Clercq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized thyroxine compounds
    Publication number: 20040116391
    Abstract: Throxinyldimethylphosphinate was invented as a prodrug to stabilize thyroxine, a drug widely used to treat hypothyroidism and depression. The presence of the dimethylphosphinate group at the phenolic hydroxyl of thyroxine is key to preventing thyroxine from decomposing through the proposed pathway. The prodrug will be hydrolyzed in the stomach or the gut into thyroxine and the biologically inert dimethylphosphinic acid. Related products may be stabilized with the same or similar protecting groups.
    Type: Application
    Filed: July 31, 2003
    Publication date: June 17, 2004
    Applicant: New River Pharmaceuticals Inc.
    Inventors: Thomas Piccariello, Anne-Frederique Le Clercq