Patents by Inventor Anne Gigout

Anne Gigout has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion protein comprising an FGF-18 moiety
    Patent number: 11572395
    Abstract: The present invention relates to new fusion proteins comprising an FGF-18 moiety fused to an anti-NGF moiety. Said fusion protein can be used for the treatment of a cartilage disorder such as osteoarthritis or cartilage injury.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: February 7, 2023
    Inventors: Anne Gigout, Christian Brenneis, Thomas Rysiok, Stefan Zielonka
  • USE OF THE GDF-5 MUTANT FOR THE TREATMENT OF PAIN AND CARTILAGE DESTRUCTION
    Publication number: 20220387556
    Abstract: The present invention is directed to the use of the GDF-5 mutant with an amino acid exchange R399E for the treatment of cartilage defects and pain and a pharmacological composition of said GDF-5 mutant.
    Type: Application
    Filed: December 15, 2020
    Publication date: December 8, 2022
    Applicant: Merck Patent GmbH
    Inventors: Kerstin KLEINSCHMIDT-DOERR, Anne GIGOUT, Daniela WERKMANN
  • FGF-18 IN GRAFT TRANSPLANTATION AND TISSUE ENGINEERING PROCEDURES
    Publication number: 20220378981
    Abstract: The present invention provides a new method related to regenerative medicine for the treatment of cartilage disorders, osteoarthritis and cartilage injury in particular. More particularly, it relates to an FGF-18 compound for use in tissue engineering and graft procedures, such as osteochondral or cartilage transplantation or autologous chondrocyte implantation (ACI).
    Type: Application
    Filed: June 16, 2022
    Publication date: December 1, 2022
    Inventors: Christoph H. LADEL, Hans GUEHRING, Anne GIGOUT
  • FUSION PROTEIN COMPRISING AN FGF-18 MOIETY
    Publication number: 20200299347
    Abstract: The present invention relates to new fusion proteins comprising an FGF-18 moiety fused to an anti-NGF moiety. Said fusion protein can be used for the treatment of a cartilage disorder such as osteoarthritis or cartilage injury.
    Type: Application
    Filed: September 20, 2018
    Publication date: September 24, 2020
    Inventors: ANNE GIGOUT, CHRISTIAN BRENNEIS, THOMAS RYSIOK, STEFAN ZIELONKA
  • CARTILAGE PRESERVATION MEDIA
    Publication number: 20200128812
    Abstract: The invention relates to the field of storage of tissues, such as transplantable material, or allograft storage, and more specifically to the field of both short- and long-term tissues storage and preservation. Preferably the tissues are transplantable material comprises chondogenic cells, such as chondrocytes, cartilage, engineered cartilage or to osteochondral/cartilage explants or fragment thereof.
    Type: Application
    Filed: March 17, 2017
    Publication date: April 30, 2020
    Inventors: ANNE GIGOUT, HANS GUEHRING, GEORGE R. DODGE, ROBERT L. MAUCK
  • COMBINATION COMPOSITION COMPRISING FGF-18 COMPOUND
    Publication number: 20180236032
    Abstract: The present invention relates to the use of an FGF-18 compound in combination with a further active ingredient, selected from the group of an inhibitor of IL-6, an inhibitor of IL-6 receptor, an inhibitor of NGF or a botulinum toxin compound. Said composition can be used for the treatment of a cartilage disorder such as osteoarthritis or cartilage injury.
    Type: Application
    Filed: August 11, 2016
    Publication date: August 23, 2018
    Inventors: CHRISTOPH H. LADEL, HANS GUEHRING, ANNE GIGOUT, CHRISTIAN BRENNEIS
  • FGF-18 IN GRAFT TRANSPLANTATION AND TISSUE ENGINEERING PROCEDURES
    Publication number: 20170056554
    Abstract: The present invention provides a new method related to regenerative medicine for the treatment of cartilage disorders, osteoarthritis and cartilage injury in particular. More particularly, it relates to an FGF-18 compound for use in tissue engineering and graft procedures, such as osteochondral or cartilage transplantation or autologous chondrocyte implantation (ACI).
    Type: Application
    Filed: February 20, 2015
    Publication date: March 2, 2017
    Inventors: CHRISTOPH H. LADEL, HANS GUEHRING, ANNE GIGOUT
  • DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS
    Publication number: 20150225369
    Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which DDR2 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: July 29, 2013
    Publication date: August 13, 2015
    Applicant: Merck Patent GmbH
    Inventors: Margarita Wucherer-Plietker, Daniela Werkmann, Anne Gigout, Daniel Kuhn, Edgar Sawatzky