Patents by Inventor Anne Hosmalin

Anne Hosmalin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for in vitro differentiation of blood circulating cells into neuronal-like cells and applications thereof
    Patent number: 9932556
    Abstract: The present invention relates to a method for in vitro differentiation of a population of blood circulating cells, such as monocytes and preferably pluripotent macrophages derived therefrom, into cells displaying functional and phenotypic neuronal characteristics. The invention further encompasses neuronal-like cells obtainable according to the present method, compositions comprising said cells, and applications thereof.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: April 3, 2018
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes, Institut Ntaitonal de la Sante et de la recherche Medicale (INSERM), Assistance Publique—Hopitaux de Paris
    Inventors: Anne Hosmalin, Vincent Feuillet, Marie-Odile Krebs, Thérèse Jay, Alfredo Bellon
  • METHOD FOR IN VITRO DIFFERENTIATION OF BLOOD CIRCULATING CELLS INTO NEURONAL-LIKE CELLS AND APPLICATIONS THEREOF
    Publication number: 20150111225
    Abstract: The present invention relates to a method for in vitro differentiation of a population of blood circulating cells, such as monocytes and preferably pluripotent macrophages derived therefrom, into cells displaying functional and phenotypic neuronal characteristics. The invention further encompasses neuronal-like cells obtainable according to the present method, compositions comprising said cells, and applications thereof.
    Type: Application
    Filed: October 16, 2014
    Publication date: April 23, 2015
    Inventors: Anne Hosmalin, Vincent Feuillet, Marie-Odile Krebs, Thérèse Jay, Alfredo Bellon
  • M-DC8+ Monocyte Depleting Agent for the Prevention or the Treatment of a Condition Associated with a Chronic Hyperactivation of the Immune System
    Publication number: 20140288279
    Abstract: The invention relates to the prevention or the treatment of a condition associated with a chronic hyperactivation of the immune system, in particular to a M-DC8+ monocyte depleting agent for the prevention or treatment of chronic inflammatory or infectious diseases.
    Type: Application
    Filed: October 19, 2012
    Publication date: September 25, 2014
    Inventors: Anne Hosmalin, Charles-Antoine Dutertre
  • Peptides stimulating cytotoxic T cells immune to HIV RT
    Patent number: 5336758
    Abstract: The subject invention relates to a peptide having the amino acid sequence Glu-Ile-Cys-Thr-Glu-Met-Glu-Lys-Glu-Gly-Lys-Ile-Ser-Lys-Ile-Gly-Pro or portions thereof. This peptide is derived from, or based upon, a region of a relatively conserved epitope of HIV-1 reverse transcriptase. The peptide may be utilized in the treatment of patients having human immunodeficiency virus or in the prevention of infection of those individuals who have been exposed to the disease, yet have not become sero-positive. The preparation containing the peptide may be administered either subcutaneously, intramuscularly or intravenously.
    Type: Grant
    Filed: March 9, 1990
    Date of Patent: August 9, 1994
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jay A. Berzofsky, Anne Hosmalin, Mario S. Clerici, Ronald N. Germain, Gene Shearer, Bernard Moss, Charles D. Pendleton
  • Synthetic vaccine against AIDS virus
    Patent number: 5030449
    Abstract: The invention relates to peptide antigens which stimulate helper T lympocytes which specifically recognize HIV envelope protein, thereby enhancing antibody production and cytotoxic T cells to inhibit expression of an infection caused by HIV virus.
    Type: Grant
    Filed: July 21, 1988
    Date of Patent: July 9, 1991
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jay A. Berzofsky, Paula M. Hale, Anne Hosmalin, Hanah Margalit, John L. Spouge, James L. Cornette