Patents by Inventor Anne J. Fulton

Anne J. Fulton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antihemophilic factor stabilization
    Patent number: 5484890
    Abstract: A method of recovering a purified and stabilized protein having antihemophilic factor activity (Factor VIII), from a biological sample containing Factor VIII, at least one destabilizing protease impurity, i.e. thrombin, and optionally one or more proprotease impurity, is provided. The biological sample is contacted with a protease removing and/or inhibiting agent, thereby inhibiting and/or removing the destabilizing protease impurity. The method provides increased yield and resolution of Factor VIII. Also provided are purified and stabilized Factor VIII non-lyophilized, liquid in compositions.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: January 16, 1996
    Inventors: Alan J. Johnson, Anne J. Fulton
  • Antihemophilic factor stabilization
    Patent number: 5278289
    Abstract: A method of recovering a purified and stabilized protein having antihemophilic factor activity (Factor VIII), from a biological sample containing Factor VIII, at least one destabilizing protease impurity, i.e. thrombin, and optionally one or more proprotease impurity, is provided. The biological sample is contacted with a protease removing and/or inhibiting agent, thereby inhibiting and/or removing the destabilizing protease impurity. The method provides increased yield and resolution of Factor VIII. Also provided are purified and stabilized Factor VIII non-lyophilized, liquid in compositions.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: January 11, 1994
    Inventors: Alan J. Johnson, Anne J. Fulton
  • Modified factor VIII
    Patent number: 4970300
    Abstract: Disclosed are conjugates of a protein having antihemophilic factor (Factor VIII) activity linked to nonantigenic ligands. The conjugates have longer half life than the unconjugated protein but maintain substantial Factor VIII activity.
    Type: Grant
    Filed: January 18, 1989
    Date of Patent: November 13, 1990
    Assignee: New York University
    Inventors: Anne J. Fulton, Alan J. Johnson