Abstract: In a method, system, and computer-readable medium having instructions for semantic matching, a configuration for one or more ontologies is determined with an ontology that has one or more concepts and a representation for the one or more concepts, and the configuration has an assignment of concepts to positions and one or more relationships between concepts in accordance with the representation. The configuration is optimized in accordance with one or more constraints, and a constraint has a relationship defined in a representation for an ontology and a judgment on a similarity of a plurality of concepts from the one or more ontologies, and an estimate is calculated for a similarity between a first concept and a second concept using the configuration.