Patents by Inventor Anne Joutel

Anne Joutel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOLOGICAL TREATMENT OF CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY
    Publication number: 20200048342
    Abstract: The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. In particular, the invention relates to an anti-Notch3 antibody or a fragment thereof having a 2 fold, 4 fold or 10 fold higher affinity to Notch 3 than to Notch 1 or Notch 2 for use in therapy.
    Type: Application
    Filed: July 23, 2019
    Publication date: February 13, 2020
    Inventors: Anne Joutel, Søren Christensen, Thorleif Jan Pedersen
  • Immunological treatment of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    Patent number: 10407500
    Abstract: The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. In particular, the invention relates to an anti-Notch3 antibody or a fragment thereof having a 2 fold, 4 fold or 10 fold higher affinity to Notch 3 than to Notch 1 or Notch 2 for use in therapy.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: September 10, 2019
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université Paris Didrerot—Paris 7
    Inventors: Anne Joutel, Søren Christensen, Thorleif Jan Pedersen
  • IMMUNOLOGICAL TREATMENT OF CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY
    Publication number: 20170247450
    Abstract: The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. In particular, the invention relates to an anti-Notch3 antibody or a fragment thereof having a 2 fold, 4 fold or 10 fold higher affinity to Notch 3 than to Notch 1 or Notch 2 for use in therapy.
    Type: Application
    Filed: September 18, 2015
    Publication date: August 31, 2017
    Inventors: Anne JOUTEL, Søren CHRISTENSEN, Thorleif Jan PEDERSEN
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Patent number: 7138234
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL and related diseases.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: November 21, 2006
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Assistance Publique-Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Patent number: 6995257
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 7, 2006
    Assignees: Institut National de la Santa et de la Recherche (INSERM), Assistance Publique - Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Publication number: 20030186290
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Application
    Filed: February 3, 2003
    Publication date: October 2, 2003
    Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-Francois Bach
  • Gene involved in cadasil, method of diagnosis and therapeutic application
    Patent number: 6537775
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: March 25, 2003
    Assignees: Institut National de la Sante et de la Recherche (INSERM), Assistance Publique - Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach