Abstract: Described herein are baculovirus vectors, host cells containing the baculovirus vectors, methods of using the baculovirus vectors for cloning genes, and kits containing the baculovirus vectors.

Abstract: Anti-EGFR antibodies, therapeutic compositions comprising combinations of anti-EGFR antibodies, as well as methods for using such antibodies and compositions to treat EGFR-related disorders (e.g., cancers), are disclosed.

Abstract: Described herein are baculovirus vectors, host cells containing the baculovirus vectors, methods of using the baculovirus vectors for cloning genes, and kits containing the baculovirus vectors.

Abstract: The application relates for method for cloning the gene comprising the steps of: 1. Providing a replication-deficient baculovirus vector, 2. Providing a rescue vector comprising (a) nucleic acid sequence which is capable of restoring replication in the replication-deficient baculovirus vector and (b) at least one gene to be cloned; 3. Causing the replication-deficient baculovirus vector and rescue vector to recombine to produce a replication-enabled baculovirus vector comprising the at least one gene to be cloned; and 4. Growing the replication-enabled baculovirus vector within a suitable invertebrate cell, such as an insect cell. Preferably the baculovirus vector is based upon AcMNPV. Also disclosed are replication-deficient baculovirus vectors, rescue vectors, cells containing such vectors and kits comprising such vectors.

Abstract: A fluid dispenser and method for applying a selected fluid to a desired location includes a reservoir containing the fluid, the reservoir includes a resilient body having a first end and a second end, a first end sealing cap, and a second end sealing cap assembly with a penetrable elastomeric member to define a reservoir interior. The body includes bellows oriented to retract or extend the body between the first end and the second end creating a variable reservoir interior volume. Also included is an applicator having a proximal end and a distal end, the proximal end includes a non coring cannula with a lumen having an insertion end adapted to penetrate through the elastomeric member and protrude into the reservoir interior. This enables fluid communication between the reservoir interior and the lumen; the distal end also includes an application element that is in fluid communication with the lumen.

Abstract: A fluid dispenser and method for applying a selected fluid to a desired location includes a reservoir containing the fluid, the reservoir includes a resilient body having a first end and a second end, a first end sealing cap, and a second end sealing cap assembly with a penetrable elastomeric member to define a reservoir interior. The body includes bellows oriented to retract or extend the body between the first end and the second end creating a variable reservoir interior volume. Also included is an applicator having a proximal end and a distal end, the proximal end includes a non coring cannula with a lumen having an insertion end adapted to penetrate through the elastomeric member and protrude into the reservoir interior. This enables fluid communication between the reservoir interior and the lumen; the distal end also includes an application element that is in fluid communication with the lumen.

Abstract: A fluid dispenser and method for applying a selected fluid to a desired location includes a reservoir containing the fluid, the reservoir includes a resilient body having a first end and a second end, a first end sealing cap, and a second end sealing cap assembly with a penetrable elastomeric member to define a reservoir interior. The body includes bellows oriented to retract or extend the body between the first end and the second end creating a variable reservoir interior volume. Also included is an applicator having a proximal end and a distal end, the proximal end includes a non coring cannula with a lumen having an insertion end adapted to penetrate through the elastomeric member and protrude into the reservoir interior. This enables fluid communication between the reservoir interior and the lumen; the distal end also includes an application element that is in fluid communication with the lumen.

Abstract: The invention relates to the use of certain pharmaceutical compounds as anti-inflammatory agents.