Patents by Inventor Anne L. Angiolillo

Anne L. Angiolillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interferon-inducible protein 10 is a potent inhibitor of angiogenesis
    Patent number: 5994292
    Abstract: The present invention is interferon-inducible protein 10 and fragments and analogs of interferon-inducible protein 10 as inhibitors of angiogenesis. The present invention is also the use of interferon-inducible protein 10 (IP-10) as well as fragments and analogs of IP-10 as potent inhibitors of angiogenesis. IP-10 profoundly inhibited basic fibroblast growth factor (bFGF)-induced neovascularization in immunocompromised mammals. In addition, IP-10, is useful in a dose-dependent fashion in suppressing endothelial cell differentiation into tubular capillary structures.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 30, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Giovanna Tosato, Anne L. Angiolillo, Cecilia Sgadari