Patents by Inventor Anne Lis Mikkelsen

Anne Lis Mikkelsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay to indicate the presence of non-fertilizable ova
    Patent number: 6649344
    Abstract: The present invention relates to an assay for at least one predictive marker in a sample from a mammal wherein a specific reaction for at least one predictive marker indicates when non-fertilizable ova capable of in vitro maturation (IVM) and subsequent in vitro fertilization (IVF) are present in the mammal. This is particularly useful in the determination of when non-fertilizable ova, if aspirated, after in vitro maturation to MF-II will be capable of fertilization and pregnancy after implantation into the female mammal. The assay is based on a sample selected from the group consisting of body secrete, sputum, blood, urine, uterus secretes and cells.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: November 18, 2003
    Assignee: Medi-Cult A/S
    Inventors: Svend Lindenberg, Anne Lis Mikkelsen
  • A METHOD FOR IN VITRO MATURATION OF HUMAN GAMETES
    Publication number: 20020115211
    Abstract: The present invention relates to a method for in vitro maturation of a human gamete by culturing an immature human gamete in a chemically defined cell culture medium. The human gamete can be a spermatocyte or an oocyte. The maturation end point is metaII. The advantage of the described medium is a synchronised cumulus-, cytoand nuclear maturation completed within a period of 20 to 30 hours. The medium should preferably contain ATA (Aurin Tri Carboxylicacid) as an anti-apototic agent. The medium should preferably not contain BSA, HSA or other directly serum derived products or substances.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 22, 2002
    Applicant: MEDI-CULT A/S
    Inventors: Svend LINDENBERG , Anne Lis MIKKELSEN , Steven Dale SMITH , Kjell BERTHEUSSEN
  • In vitro maturation of human oocytes in one day
    Publication number: 20010028878
    Abstract: The present invention relates to a method for in vitro maturation of a human oocyte by culturing an immature human oocyte in a cell culture medium for 10-30 hours. The maturation end point is metaphase II.
    Type: Application
    Filed: December 22, 2000
    Publication date: October 11, 2001
    Inventors: Svend Lindenberg, Anne Lis Mikkelsen, Steven Dale Smith, Kjell Bertheussen