Patents by Inventor Anne-Lise Borresen

Anne-Lise Borresen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE SIGNATURES ASSOCIATED WITH EFFICACY OF POSTMASTECTOMY RADIOTHERAPY IN BREAST CANCER
    Publication number: 20150111758
    Abstract: The present invention relates to compositions, kits, and methods for providing a prognosis and/or determining a treatment course of action in a subject diagnosed with breast cancer. In particular, the present invention relates to gene expression signatures useful in the prognosis, diagnosis, and treatment of breast cancer.
    Type: Application
    Filed: March 6, 2013
    Publication date: April 23, 2015
    Inventors: Therese Sorlie, Arnoldo Frigessi, Anne-Lise Borresen-Dale, Simen Myhre, Hayat Mohammed, Jens Overgaard, Jan Alsner, Trine Tramm
  • Method and apparatus for detecting single base mutations in DNA with denaturing gradient electrophoresis
    Patent number: 5190856
    Abstract: Single base pair differences between otherwise identical DNA fragments can result in an altering of the melting behavior which can be detected by denaturing gradient gelelectrophoresis (DGGE). A method has been developed for efficient transfer of genomic DNA fragments from the gel following DGGE. The DGGE is run in a polyacrylamide gel (PAG) containing 2% low gelling temperature agarose (LGT). The PAG is crosslinked with a reversible crosslinker, and after electrophoresis the crosslinks are cleaved and 80-100% of the DNA fragments are transferred to nylon membranes by alkaline transfer. Hybridization with gene specific probes is then performed. The technique has been used to identify an RFLP in the COLIA2 gene.
    Type: Grant
    Filed: May 31, 1989
    Date of Patent: March 2, 1993
    Inventor: Anne-Lise Borresen