Patents by Inventor Anne M. Cataldo

Anne M. Cataldo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY
    Publication number: 20200316115
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Application
    Filed: January 6, 2020
    Publication date: October 8, 2020
    Inventors: Anne M. Cataldo, Bruce M. COHEN
  • METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY
    Publication number: 20180071337
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Application
    Filed: October 18, 2017
    Publication date: March 15, 2018
    Applicant: The McLean Hospital Corporation
    Inventors: Anne M. CATALDO (Deceased), Bruce M. COHEN
  • Methods and compositions for mitochondrial replacement therapy
    Patent number: 9855296
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: January 2, 2018
    Assignee: The McLean Hospital Corporation
    Inventors: Anne M. Cataldo, Bruce M. Cohen
  • Methods and compositions for mitochondrial replacement therapy
    Patent number: 9603872
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: March 28, 2017
    Assignee: The McLeon Hospital Corporation
    Inventors: Anne M. Cataldo, Peter A. Paskevich, Bruce M. Cohen
  • METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY
    Publication number: 20170065635
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Application
    Filed: November 16, 2016
    Publication date: March 9, 2017
    Inventors: Anne M. CATALDO, Bruce M. COHEN
  • METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY
    Publication number: 20110008310
    Abstract: The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.
    Type: Application
    Filed: May 2, 2008
    Publication date: January 13, 2011
    Applicant: The McLean Hospital Corporation
    Inventors: Anne M. Cataldo, Peter A. Paskevich, Bruce M. Cohen
  • Methods for the identification of compounds for the treatment of neuronal atrophy-associated dementia
    Patent number: 7090987
    Abstract: The invention features methods of diagnosing and treating a patient having Alzheimer's disease or other neuronal atrophy-associated dementia by determining or altering, respectively, the level of activity of pathways from the endoplasmic reticulum to lysosomes in the patient.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: August 15, 2006
    Inventors: Ralph A. Nixon, Anne M. Cataldo, Paul M. Mathews
  • Methods for the identification of compounds for the treatment of alzheimer's disease
    Patent number: 6838592
    Abstract: The invention features methods for identifying compounds useful for the treatment of Alzheimer's disease.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: January 4, 2005
    Assignee: Nathan S. Kline Institute for Psychiatric Research
    Inventors: Ralph A. Nixon, Anne M. Cataldo, Paul M. Mathews
  • Use of presenilin-1 for diagnosis of alzheimers disease
    Patent number: 5985581
    Abstract: The invention provides a method of diagnosing Alzheimer's disease. The method utilizes presenilin-1, whose level is found to be substantially decreased in Alzheimer's patients. Included in the invention are diagnostic kits for Alzheimer's disease and methods of screening for effective therapeutics for the disease. The invention also provides a method of studying the function and regulation of presenilin-1 in brain by the use of primate retinoblastoma cells.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 16, 1999
    Assignee: The McLean Hospital Corporation
    Inventors: Ralph A. Nixon, Anne M. Cataldo, Benjamin H. Kao, Paul M. Mathews