Patents by Inventor Anne M. Hooke

Anne M. Hooke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
    Patent number: 4681762
    Abstract: The present invention relates to a vaccine composition for the prevention of infectious diseases comprising an immunogenically-effective amount of a genetically attenuated and stable avirulent bacterial strain derived from a virulent bacterial strain by introducing into said virulent strain by genetic transfer and recombination at least two mutations of the same phenotype which renders said virulent strain avirulent, while permitting said avirulent strain to retain immunogenicity, together with an inert pharmacologically acceptable carrier. It also relates to a method for preparing the vaccine.
    Type: Grant
    Filed: February 16, 1984
    Date of Patent: July 21, 1987
    Assignee: Research Corporation
    Inventors: Max P. Oeschger, Anne M. Hooke, Joseph A. Bellanti
  • Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
    Patent number: 4337314
    Abstract: A vaccine composition comprising a genetically attenuated bacterial strain which contains at least two mutations of the same phenotype which strain is rendered avirulent while retaining immunogenicity.
    Type: Grant
    Filed: May 23, 1979
    Date of Patent: June 29, 1982
    Assignee: Research Corporation
    Inventors: Max P. Oeschger, Anne M. Hooke, Joseph A. Bellanti