Patents by Inventor Anne Marie Horneman

Anne Marie Horneman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing ingenol-3-angelate
    Patent number: 9676698
    Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: June 13, 2017
    Assignee: LEO Laboratories Limited
    Inventors: Thomas Hogberg, Gunnar Grue-Sorensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
  • METHOD OF PRODUCING INGENOL-3-ANGELATE
    Publication number: 20160280627
    Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.
    Type: Application
    Filed: June 9, 2016
    Publication date: September 29, 2016
    Inventors: Thomas Hogberg, Gunnar Grue-Sorensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
  • Method of producing ingenol-3-angelate
    Patent number: 9416084
    Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: August 16, 2016
    Assignee: LEO Laboratories Limited
    Inventors: Thomas Hogberg, Gunnar Grue-Sorensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
  • Biaryl phosphodiesterase inhibitors
    Patent number: 9051290
    Abstract: Novel biaryl compounds with phosphodiesterase inhibitory activity of general formula (I) below, wherein R1, R2, R3, X, Y, Z1, Z2, Z3, and Z4 have the meanings defined herein, as well as their use as therapeutic agents in the treatment of inflammatory diseases and conditions are described herein.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: June 9, 2015
    Assignee: LEO PHARMA A/S
    Inventors: Simon Feldbæk Nielsen, Anne Marie Horneman, Jesper Lau, Jens Christian Højland Larsen
  • Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases
    Patent number: 8952162
    Abstract: The present invention relates to a compound according to formula I, wherein R1, R2 and A are as defined herein, which exhibit PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases, in particular inflammatory or proliferative dermal diseases.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: February 10, 2015
    Assignee: Leo Pharma A/S
    Inventors: Simon Feldbæk Nielsen, Thomas Vifian, Anne Marie Horneman, Jesper Færgemann Lau
  • Method of producing ingenol-3-angelate
    Patent number: 8901356
    Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: December 2, 2014
    Assignee: Leo Laboratories Limited
    Inventors: Thomas Högberg, Gunnar Grue-Sørensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
  • METHOD OF PRODUCING INGENOL-3-ANGELATE
    Publication number: 20130177952
    Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.
    Type: Application
    Filed: July 8, 2011
    Publication date: July 11, 2013
    Inventors: Thomas Högberg, Gunnar Grue-Sørensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
  • BIARYL PHOSPHODIESTERASE INHIBITORS
    Publication number: 20130059853
    Abstract: Novel biaryl compounds with phosphodiesterase inhibitory activity of the general formula (I), wherein R1, R2, R3, X, Y, Z1, Z2, Z3, and Z4 have the meanings defined herein, as well as their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
    Type: Application
    Filed: April 28, 2011
    Publication date: March 7, 2013
    Applicant: LEO PHARMA A/S
    Inventors: Simon Feldbaek Nielsen, Anne Marie Horneman, Jesper Lau, Jens Christian Hojland Larsen
  • VEGF-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereof
    Patent number: 8350026
    Abstract: The invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R1, R2, R3, R4, R5 and Y are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for treating diseases associated with deregulated angiogenesis, such as cancer and skin and eye diseases.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: January 8, 2013
    Assignee: Leo Pharma A/S
    Inventors: Jakob Felding, Xifu Liang, Anne Marie Horneman, Tina Dahlerup Poulsen, Jens Christian Højland Larsen
  • TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES
    Publication number: 20120028974
    Abstract: The present invention relates to a compound according to formula I, wherein R1, R2 and A are as defined herein, which exhibit PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases, in particular inflammatory or proliferative dermal diseases.
    Type: Application
    Filed: December 18, 2009
    Publication date: February 2, 2012
    Applicant: LEO PHARMA A/S
    Inventors: Simon Feldbaek Nielsen, Thomas Vifian, Anne Marie Horneman, Jesper Faergemann Lau
  • NOVEL VEGF-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF
    Publication number: 20110190282
    Abstract: The invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R1, R2, R3, R4, R5 and Y are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for treating diseases associated with deregulated angiogenesis, such as cancer and skin and eye diseases.
    Type: Application
    Filed: August 27, 2009
    Publication date: August 4, 2011
    Applicant: LEO PHARMA A/S
    Inventors: Jakob Felding, Xifu Liang, Anne Marie Horneman, Tina Dahlerup Poulsen, Jens Christian Højland Larsen
  • Aminobenzophenone compounds
    Patent number: 7977387
    Abstract: The invention provides novel compounds according to formula I relates to compounds with the general formula I said compounds being useful, e.g. in the treatment of inflammatory, ophthalmic diseases or cancer.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: July 12, 2011
    Assignee: Leo Pharma A/S
    Inventors: Erik Rytter Ottosen, Anne Marie Horneman, Xifu Liang, Søren Christian Schou, Sophie Elisabeth Havez, Thomas Peter Sabroe
  • Aminobenzoephenones
    Patent number: 7034015
    Abstract: The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said compounds in the manufacture of pharmaceutical preparations.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: April 25, 2006
    Assignee: Leo Pharma A/S
    Inventors: Erik Rytter Ottosen, Anne Marie Horneman, Xifu Liang
  • Novel aminobenzoephenones
    Publication number: 20030119902
    Abstract: The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said compounds in the manufacture of pharmaceutical preparations.
    Type: Application
    Filed: August 28, 2002
    Publication date: June 26, 2003
    Inventors: Erik Rytter Ottosen, Anne Marie Horneman, Xifu Liang
  • Benzophenones as inhibitors of IL-1&bgr; and TNF-&agr;
    Patent number: 6432962
    Abstract: Heteroaryl aminobenzophenones of general formula I inhibit interleukin-1&bgr; and TNF-&agr; and may therefore be useful in the therapy of inflammatory diseases and conditions.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: August 13, 2002
    Assignee: Leo Pharmaceutical Products Ltd. A/S
    Inventor: Anne Marie Horneman
  • Benzophenones as inhibitors of IL-1beta and TNF-alpha
    Publication number: 20020016347
    Abstract: Heteroaryl aminobenzophenones of general formula I inhibit interleukin-1&bgr; and TNF-&agr; and may therefore be useful in the therapy of inflammatory diseases and conditions.
    Type: Application
    Filed: May 21, 2001
    Publication date: February 7, 2002
    Inventor: Anne Marie Horneman