Patents by Inventor Anne Marie Jeanne Bouillot

Anne Marie Jeanne Bouillot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS
    Publication number: 20130281499
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Application
    Filed: June 21, 2013
    Publication date: October 24, 2013
    Inventors: Anne Marie Jeanne BOUILLOT, Alain Laroze, Lionel Trottet
  • Imidazo [4, 5-C] quinoline derivatives as bromodomain inhibitors
    Patent number: 8557984
    Abstract: Novel compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: October 15, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Anne Marie Jeanne Bouillot, Frederic Donche, Francoise Jeanne Gellibert, Yann Lamotte, Olivier Mirguet
  • 1,2,3-triazole derivatives for use as stearoyl-CoA desaturase inhibitors
    Patent number: 8486977
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: July 16, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Anne Marie Jeanne Bouillot, Alain Laroze, Lionel Trottet
  • PYRROLO [3,2-D] PYRIMIDIN-3-YL DERIVATIVES USED AS ACTIVATORS OF AMPK
    Publication number: 20130053407
    Abstract: Pyrrolopyrimidones compounds of the formula (I), salts thereof, and pharmaceutical compositions containing them are disclosed herein, as well as methods for their use in medicine, for instance as activators of AMPK.
    Type: Application
    Filed: May 3, 2011
    Publication date: February 28, 2013
    Applicant: GlaxoSmithKline LLC
    Inventors: Olivier Mirguet, Anne Marie Jeanne Bouillot
  • Imidazo [4, 5-C] Quinoline Derivatives As Bromodomain Inhibitors
    Publication number: 20120232074
    Abstract: Novel compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: September 13, 2012
    Inventors: Anne Marie Jeanne Bouillot, Frederic Donche, Francoise Jeanne Gellibert, Yann Lamotte, Olivier Mirguet
  • COMPOUNDS
    Publication number: 20120225878
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity.
    Type: Application
    Filed: May 15, 2012
    Publication date: September 6, 2012
    Inventors: Anne Marie Jeanne BOUILLOT, Alain LAROZE
  • Triazole derivatives as SCD inhibitors
    Patent number: 8207204
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer and the treatment of symptoms linked to the production of the amyloid plaque-forming A?42 peptide such as Alzheimer's disease and the like.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: June 26, 2012
    Assignee: GlaxoSmithKline LLC
    Inventors: Anne Marie Jeanne Bouillot, Alain Laroze
  • 1,2,3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS
    Publication number: 20100297054
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Application
    Filed: November 7, 2008
    Publication date: November 25, 2010
    Inventors: Anne Marie Jeanne Bouillot, Alain Laroze, Lionel Trottet
  • COMPOUNDS
    Publication number: 20100297097
    Abstract: The present invention relates to substituted triazole compounds of the formula (I): and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer and the treatment of symptoms linked to the production of the amyloid plaque-forming A?42 peptide such as Alzheimer's disease and the like.
    Type: Application
    Filed: November 7, 2008
    Publication date: November 25, 2010
    Inventors: Anne Marie Jeanne Bouillot, Alain Laroze
  • THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE
    Publication number: 20100120669
    Abstract: The present invention relates to substituted thiadiazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Application
    Filed: February 26, 2008
    Publication date: May 13, 2010
    Inventors: Anne Marie Jeanne Bouillot, Thierry Boyer, Alain Claude-Marie Daugan, Anthony William Dean, Martin Christian Fillmore, Yann Lamotte
  • Compounds
    Publication number: 20100041590
    Abstract: The present invention relates to substituted 3-Aminopyrazole compounds of formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Application
    Filed: December 19, 2007
    Publication date: February 18, 2010
    Inventor: Anne Marie Jeanne Bouillot
  • COMPOUNDS
    Publication number: 20100022486
    Abstract: The present invention relates to substituted 3-Aminopyrazole compounds of formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
    Type: Application
    Filed: December 19, 2007
    Publication date: January 28, 2010
    Inventors: Anne Marie Jeanne Bouillot, Alain Claude-Marie Daugan, Anthony William Dean, Martin Christian Fillmore
  • Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression
    Publication number: 20040077654
    Abstract: The invention concerns Use of a compound of formula (I) or a physiologically acceptable salt, solvate or derivative thereof, in the manufacture of a medicament for the treatment of diseases ameliorated by LDL-r upregulation, to novel compounds and pharmaceutical compositions within the scope of formula (I).
    Type: Application
    Filed: November 11, 2003
    Publication date: April 22, 2004
    Inventors: Anne Marie Jeanne Bouillot, Agnes Bombrun, Bernard Andre Dumaitre, Romain Luc Gosmini, Miles Stuart Congreve, Nigel Grahame Ramsden
  • Aryl piperidine derivatives as inducers of ldl-receptor expression
    Publication number: 20040072865
    Abstract: The invention concerns a compound of formula (I), wherein Ar1 represents phenyl, naphthyl or phenyl fused by a C3-8cycloalkyl, where each group is substituted by a group —O-Z and optionally one to three further groups independently represented by R1; Ar2 represents phenyl or 5-6 membered heteroaromatic group, where each group is optionally substituted by one to four groups independently selected from halogen, C1-4 alkyl and C1-4 alkoxy; Ar3 represents a phenyl or a 5-6 membered heteroaromatic group, where each group is optionally substituted by one to four groups independently selected from hydroxy, alkyl, C1-4 alkoxy, C2-4 alkenyl, C2-4 alkenyloxy, C1-4 perfluoroalkoxy, C1-4 acylamino or an electron withdrawing group; A represents —C(H)—; E represents —C1-6alkylene-; X represents —CON(H or C1-4alkyl)- or —N(H or C1-4alkyl)CO—; Y represents a direct link, —N(H or C1-4alkyl)CO— or —CON(H or C1-4alkyl)-; Z represents a metabolically labile group; R1 re
    Type: Application
    Filed: October 20, 2003
    Publication date: April 15, 2004
    Inventors: Anne Marie Jeanne Bouillot, Agnes Bombrun, Bernard Andre Dumaitre, Rontain Luc Gosmini, Miles Stuart Congreve, Nigel Grahame Ramsden