Abstract: Compounds and methods are provided for treating bacterial infections.

Abstract: The present invention relates to polycyclic antiviral compounds, and salts thereof, methods for their preparation and compositions containing them, and the use of the compounds and composition in the treatment of viral infections.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to compounds of formula (I) or salts, racemates, isomers and/or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial viral (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to compounds of formula (I), racemates, isomers and/or salts thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds.

Abstract: The present invention relates to compounds of formula (I) or salts, racemates, isomers and/or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial viral (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to polycyclic antiviral compounds, and salts thereof, methods for their preparation and compositions containing them, and the use of the compounds and composition in the treatment of viral infections.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: The present invention relates to polycyclic antiviral compounds, and salts thereof, methods for their preparation and compositions containing them, and the use of the compounds and composition in the treatment of viral infections.

Abstract: The present invention relates to compounds of formula (I), racemates, isomers and/or salts thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds.

Abstract: The present invention relates to compounds of formula (I) its salts, isomers or prodrugs thereof useful in the treatment of viral infections, in particular respiratory syncytial virus (RSV) infections. The present invention also relates to processes for preparing the compounds and intermediates used in their preparation.

Abstract: A method and system for the management of deletion requests for related documents in a content management system. When a user requests to delete a related document associated with a record in the content management system, the request determines whether there are other documents associated with the record, collects the documents and determines if any of the collected documents are parent documents, removes the association between each collected document and the record, and initiates a deletion process to delete the parent documents.

Abstract: The present invention relates to polycyclic antiviral compounds, and salts thereof, methods for their preparation and compositions containing them, and the use of the compounds and composition in the treatment of viral infections.

Abstract: A method and system for the management of deletion requests for related documents in a content management system. When a user requests to delete a related document associated with a record in the content management system, the request determines whether there are other documents associated with the record, collects the documents and determines if any of the collected documents are parent documents, removes the association between each collected document and the record, and initiates a deletion process to delete the parent documents.

Abstract: The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride) (PVDF), and chlorinated polypropylene (cPP). Resulting polymers include comb polymers which can have a microphase-separated structure of hydrophilic domains provided by the hydrophilic chains. Articles prepared from these comb polymers, particularly derived from PVDF, include membranes for water filtration in which the hydrophilic domains provide a pathway for water transport. PVC can be plasticized by grafting the PVC with hydrophilic chains. In addition, such articles, particularly articles having biomedical applications, can display anti-thrombogenic properties.

Abstract: The present invention provides a series of baroplastic materials, and systems and methods of making and using such baroplastic materials. In one aspect of the invention, polymeric particles are provided that can be used to produce baroplastic materials under certain pressures and/or below certain temperatures. In one set of embodiments, the polymeric particles include an inner “core” region and an outer “shell” region. In some cases, more than one “shell” region may be present. In another arrangement the particles can include materials, or domains, in nanoscale proximity with each other. Non-particulate materials can also be processed in accordance with the invention. In another aspect of the invention, the invention provides for polymeric particles that can be processed and/or recycled multiple times, without causing significant degradation or alteration in the physical and/or chemical properties of the polymer.

Abstract: This invention relates to methods of making graft copolymers, and articles having such graft copolymers. The methods may provide better control than in radicalization or photoinitiated polymerization techniques. For example, a graft copolymer can be prepared by reacting an alkoxide ion with a polymer. The alkoxide, in turn, can be provided by any suitable technique, for example, by reacting an alcohol with a base. In some embodiments of the invention, the graft copolymers may be a normally hydrophobic polymer, such as a polysulfone, that has been made more hydrophilic due to the attachment of hydrophilic side groups such as polyethylene glycol or polypropylene glycol. The copolymers of the invention have many uses, for example, in films or porous membranes.