Patents by Inventor Anne McLeod

Anne McLeod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conformation-specific anti-von Willebrand factor antibodies
    Publication number: 20040109858
    Abstract: The present invention is directed to antibodies and antibody fragments that bind specifically to the active conformation of human von Willebrand factor. Most preferred are recombinantly produced single chain variable immunoglobulin fragments. Because the antibodies or antibody fragments act only at the sites of thrombus formation and do not interfere with the normal activity of circulating platelets, they are particularly well suited for use as antithrombotic agents in a wide variety of applications.
    Type: Application
    Filed: June 20, 2003
    Publication date: June 10, 2004
    Applicant: Brigham and Women's Hospital, Inc.
    Inventors: Robert I. Handin, Huabing Yuan, Anne McLeod
  • Conformation-specific anti-von Willebrand factor antibodies
    Patent number: 6605277
    Abstract: The present invention is directed to antibodies and antibody fragments that bind specifically to the active conformation of human von Willebrand factor. Most preferred are recombinantly produced single chain variable immunoglobulin fragments. Because the antibodies or antibody fragments act only at the sites of thrombus formation and do not interfere with the normal activity of circulating platelets, they are particularly well suited for use as antithrombotic agents in a wide variety of applications.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: August 12, 2003
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Robert I. Handin, Huabing Yuan, Anne McLeod
  • Conformation-specific anti-von Willebrand factor antibodies
    Publication number: 20010024647
    Abstract: The present invention is directed to antibodies and antibody fragments that bind specifically to the active conformation of human von Willebrand factor. Most preferred are recombinantly produced single chain variable immunoglobulin fragments. Because the antibodies or antibody fragments act only at the sites of thrombus formation and do not interfere with the normal activity of circulating platelets, they are particularly well suited for use as antithrombotic agents in a wide variety of applications.
    Type: Application
    Filed: April 6, 2001
    Publication date: September 27, 2001
    Inventors: Robert I. Handin, Huabing Yuan, Anne McLeod
  • Conformation-specific anti-von Willebrand Factor antibodies
    Patent number: 6251393
    Abstract: The present invention is directed to antibodies and antibody fragments that bind specifically to the active conformation of human von Willebrand factor. Most preferred are recombinantly produced single chain variable immunoglobulin fragments. Because the antibodies or antibody fragments act only at the sites of thrombus formation and do not interfere with the normal activity of circulating platelets, they are particularly well suited for use as antithrombotic agents in a wide variety of applications.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: June 26, 2001
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Robert I. Handin, Huabing Yuan, Anne McLeod