Patents by Inventor Anne Messer

Anne Messer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Controlled Protein Degradation in Neurodegenerative Disease
    Publication number: 20240009285
    Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an antigen binding domain (e.g., anti-synuclein, anti-tau, anti-huntingtin) and a second domain comprising a programmable proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of protein aggregation diseases, e.g., neurodegenerative diseases.
    Type: Application
    Filed: November 11, 2021
    Publication date: January 11, 2024
    Inventors: David Butler, Anne Messer, Sally Temple
  • Bi-functional anti-tau polypeptides and use thereof
    Patent number: 11827683
    Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an anti-tau antigen binding domain and a second domain comprising a proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of tauopathies.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: November 28, 2023
    Assignee: Regenerative Research Foundation
    Inventors: Sally Temple, Anne Messer, David Butler
  • Bi-Functional Anti-Tau Polypeptides and Use Thereof
    Publication number: 20220002365
    Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an anti-tau antigen binding domain and a second domain comprising a proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of tauopathies.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 6, 2022
    Inventors: Sally Temple, Anne Messer, David Butler
  • Bi-functional anti-tau polypeptides and use thereof
    Patent number: 11072639
    Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an anti-tau antigen binding domain and a second domain comprising a proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of tauopathies.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: July 27, 2021
    Assignee: Regenerative Research Foundation
    Inventors: Sally Temple, Anne Messer, David Butler
  • Bi-Functional Anti-Tau Polypeptides and Use Thereof
    Publication number: 20190202879
    Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an anti-tau antigen binding domain and a second domain comprising a proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of tauopathies.
    Type: Application
    Filed: September 8, 2017
    Publication date: July 4, 2019
    Inventors: Sally Temple, Anne Messer, David Butler
  • Methods and compositions for inhibiting polypeptide accumulation associated with neurological disorders
    Publication number: 20050255113
    Abstract: The invention provides methods for inhibiting the formation of undesired intracellular polypeptide complexes or aggregates associated with neurological disorders using an intrabody.
    Type: Application
    Filed: September 27, 2004
    Publication date: November 17, 2005
    Inventors: James Huston, Anne Messer, Jean-Michel Lecerf