Abstract: Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

Abstract: A collapsible umbrella gym for an infant or toddler which is highly portable, and combines the desirable attributes of an activity arch and support mat such as an activity mat. The gym comprises a frame assembly which is selectively movable between collapsed and uncollapsed states. When in its fully deployed, uncollapsed state, the frame assembly assumes a configuration which provides the functional attributes of an activity gym or activity arch, with multiple toys or mobiles being suspended from the frame assembly at locations which are easily accessible to an infant or toddler lying underneath the frame assembly.

Abstract: A compound of formula (I): M-L-M, wherein L is a linker and each M is independently a group of formula (II): is useful in therapy, e.g. of respiratory diseases.

Abstract: The present invention relates generally to a method of diagnosing, predicting or monitoring the development or progress of a condition characterised by modulation in the level of activin expression and, more particularly, a method of diagnosing, predicting or monitoring the development or progress of a condition characterised by modulation in the level of expression of activin bc subunit. The present invention still further provides methods for the therapeutic or prophylactic treatment of conditions characterised by aberrant, unwanted or otherwise inappropriate activin expression, for example, conditions characterised by over-expression or underexpression of activin and most particularly, conditions characterised by overexpression or underexpression of activin bc subunit. A further aspect of the present invention extends to agents for use in the methods of the present invention.

Abstract: Methods and compositions for modulating activin dimer formation, such as the formation of activin dimers formed by the dimerisation of activin subunits ?A, ?B, ?C, ?D, or ?E, or combinations thereof, are provided. The invention also relates to methods and compositions for detecting an activin monomer or dimer using, for example, an antibody. Methods and compositions for diagnosing and/or prognosing, preventing or treating conditions and/or diseases associated with activin dimer formation, such as prostate cancer, are disclosed.