Patents by Inventor Anne Schaefer

Anne Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250075215
    Abstract: Provided are compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method includes administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Application
    Filed: November 18, 2024
    Publication date: March 6, 2025
    Applicants: Icahn School of Medicine at Mount Sinai, The Rockefeller University
    Inventors: Anne SCHAEFER, Paul GREENGARD, Chan Lek TAN
  • Patent number: 12163130
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: December 10, 2024
    Assignees: Icahn School of Medicine at Mount Sinai, The Rockefeller University
    Inventors: Anne Schaefer, Paul Greengard, Chan Lek Tan
  • Publication number: 20220305027
    Abstract: The present disclosure relates to a method of inducing a neuroprotective state comprising administering a Bromodomain and Extra-Terminal motif (BET) inhibitor under conditions effective to induce a neuroprotective state. Also disclosed are methods of preventing and/or treating neurodegenerative disease, methods of reducing microglial inflammation, and methods of restoring microglial homeostasis, where the methods include administering a Bromodomain and Extra-Terminal motif (BET) inhibitor.
    Type: Application
    Filed: May 4, 2020
    Publication date: September 29, 2022
    Inventors: Anne SCHAEFER, Josefa SULLIVAN, Alexander TARAKHOVSKY, Uwe SCHAEFER, Tuo ZHANG
  • Publication number: 20210317451
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Application
    Filed: November 16, 2020
    Publication date: October 14, 2021
    Inventors: Anne SCHAEFER, Paul GREENGARD
  • Patent number: 10947546
    Abstract: Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The methods provided herein facilitate the analysis of gene expression in the selected subset present within a heterogeneous sample.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 16, 2021
    Assignee: The Rockefeller University
    Inventors: Nathanial Heintz, Paul Greengard, Myriam Heiman, Anne Schaefer, Joseph P. Doyle, Joseph D. Dougherty
  • Patent number: 10870853
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 22, 2020
    Assignees: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE ROCKEFELLER UNIVERSITY
    Inventors: Anne Schaefer, Paul Greengard
  • Publication number: 20190144858
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Application
    Filed: October 1, 2018
    Publication date: May 16, 2019
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE ROCKEFELLER UNIVERSITY
    Inventors: Anne SCHAEFER, Paul GREENGARD
  • Patent number: 10087443
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: October 2, 2018
    Assignees: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE ROCKEFELLER UNIVERSITY
    Inventors: Anne Schaefer, Paul Greengard
  • Publication number: 20180155728
    Abstract: Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The methods provided herein facilitate the analysis of gene expression in the selected subset present within a heterogeneous sample.
    Type: Application
    Filed: September 29, 2017
    Publication date: June 7, 2018
    Inventors: Nathanial Heintz, Paul Greengard, Myriam Heiman, Anne Schaefer, Joseph P. Doyle, Joseph D. Dougherty
  • Patent number: 9816096
    Abstract: Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The methods provided herein facilitate the analysis of gene expression in the selected subset present within a heterogeneous sample.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: November 14, 2017
    Assignee: THE ROCKEFELLER UNIVERSITY
    Inventors: Nathaniel Heintz, Paul Greengard, Myriam Heiman, Anne Schaefer, Joseph P. Doyle, Joseph D. Dougherty
  • Publication number: 20160244757
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Application
    Filed: October 28, 2014
    Publication date: August 25, 2016
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE ROCKEFELLER UNIVERSITY
    Inventors: Anne SCHAEFER, Paul GREENGARD
  • Publication number: 20150082470
    Abstract: Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The methods provided herein facilitate the analysis of gene expression in the selected subset present within a heterogeneous sample.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventors: Nathaniel HEINTZ, Paul GREENGARD, Myriam HEIMAN, Anne SCHAEFER, Joseph P. DOYLE, Joseph D. DOUGHERTY
  • Patent number: 8191189
    Abstract: In general, various embodiments of the present invention disclose swaddling implements and/or blankets that immobilize an infant's arms while placing gentle, even pressure on the torso, restricting leg movement without excessive pressure, and leaving the infant's head unencumbered.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: June 5, 2012
    Inventor: Leigh Anne Schaefer Spell
  • Publication number: 20110071049
    Abstract: Methods and compositions are provided for translational profiling and molecular phenotyping of specific tissues, cells and cell subtypes of interest. The methods provided herein facilitate the analysis of gene expression in the selected subset present within a heterogeneous sample.
    Type: Application
    Filed: March 12, 2009
    Publication date: March 24, 2011
    Inventors: Nathaniel Heintz, Paul Greengard, Myriam Heiman, Anne Schaefer, Joseph P. Doyle, Joseph D. Dougherty
  • Patent number: RE50507
    Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
    Type: Grant
    Filed: February 4, 2022
    Date of Patent: July 29, 2025
    Assignees: Icahn School of Medicine at Mount Sinai, The Rockefeller University
    Inventors: Anne Schaefer, Paul Greengard, Chan Lek Tan