Abstract: Systems and methods for modifying imposition parameters using dynamically loaded media sizes. A print job is received into a computerized device comprising a marking device. The print job comprises an electronic document and print job attributes and imposition defining an arrangement of images in the electronic document for predefined dimensions of continuous feed print media. A change in print media being fed into the marking device is automatically detected, using the computerized device. The print job attributes are automatically modified, using the computerized device, based on the change in the print media, without further operator intervention.

Abstract: Systems and methods for modifying imposition parameters using dynamically loaded media sizes. A print job is received into a computerized device comprising a marking device. The print job comprises an electronic document and print job attributes and imposition defining an arrangement of images in the electronic document for predefined dimensions of continuous feed print media. A change in print media being fed into the marking device is automatically detected, using the computerized device. The print job attributes are automatically modified, using the computerized device, based on the change in the print media, without further operator intervention.

Abstract: The present invention provides isolated polynucleotides encoding a receptor gene called GPR50 having at least one polymorphic sites. It furthermore provides a method for analyzing polymorphic sites in the receptor gene. Certain of these polynucleotides having a polymorphic site (allelic variants) are found to be more prevelant in a population of patients with clinical Bipolar Depression compared to a control population. A method for the genetic testing of Bipolar Depression is a further embodiment of the present invention. Furthermore, polynucleotides encompassing these polymorphic sites, the invariant distal or proximal to the polymorphic site localized polynucleotides as well as the polynucleotides encoding CPR50 are part of the invention. The present invention also provides a recombinant cell line expressing these novel receptors at appropriate levels such that novel compounds active at these receptors may be identified for therapeutic use.

Abstract: A method for promoting bodily fluid expression from a target site includes urging a target site of a user's body toward a device for promoting expression of bodily fluid from the target site. The method also includes sequentially increasing an area of contact and applied pressure between a pressure application mechanism of the device and the user's body in the vicinity of the target site, and in a direction toward the target site, thereby urging bodily fluid toward the target site. Thereafter, the target site is lanced.

Abstract: A device for promoting the expression of bodily fluid from a target site on a user's body includes a base and a pressure application mechanism. The pressure application mechanism is attached to the base and urges bodily fluid toward the target site. The pressure application mechanism configured for urging the bodily fluid by sequentially increasing an area of contact and applied pressure between the pressure application mechanism and the user's body in the vicinity of the target site. Moreover, the area of contact and applied pressure sequentially increases in a direction toward the target site.

Abstract: An analyte monitoring system for the determination of an analyte in a bodily fluid sample includes a housing, a meter for the determination of an analyte in a bodily fluid sample, and a device for promoting the expression of the bodily fluid sample from a target site. The device for promoting expression of bodily fluid has a pressure application mechanism for urging bodily fluid toward the target site attached to the housing. In addition, the pressure application mechanism is configured for urging the bodily fluid by sequentially increasing an area of contact and applied pressure between the pressure application mechanism and the user's body in the vicinity of the target site with the area of contact and applied pressure sequentially increasing in a direction toward the target site.

Abstract: A cap for use with a dermal tissue lancing device (that includes a housing and a lancet movable with respect to the housing) includes a proximal end for engaging with the housing, a distal end for engaging with dermal tissue and an opening for a portion of the lancet to pass through. The distal end of the cap includes portions for engaging dermal tissue. These portions are resiliently deformable such that, when the cap contacts and is urged towards dermal tissue, the portions deform resiliently, engaging the dermal tissue and approaching theretogether. A process for the collection of a fluid sample (e.g., blood) from dermal tissue includes providing a dermal tissue lancing device with a housing, a cap and a lancet that is moveable with respect to the housing and the cap. The cap includes a proximal end for engaging with the housing, a distal end for engaging with dermal tissue, and an opening for a portion of the lancet to pass through.

Abstract: The present invention provides isolated polynucleotides encoding a receptor gene called GPR50 having at least one polymorphic sites. It furthermore provides a method for analysing polimorphic sites in said receptor gene. Certain of these polynucleotides having a polymorphic site (allelic variants) are found to be more prevalent in a population of patients with clinical Bipolar Depression compared to a control population. A method for the genetic testing of Bipolar Depression is a further embodiment of the present invention. Furthermore, polynucleotides encompassing these polymorphic sites, the invariant distal or proximal to the polymorphic site localized polynucleotides as well as the polynucleotides encoding GPR50 are part of the invention. The present invention also provides a recombinant cell line expressing these novel receptors at appropriate levels such that novel compounds active at these receptors may be identified for therapeutic use.

Abstract: A mouldable photographic material is made up from a thermoplastic base sheet, and a primer coating which provides the key for a photographic emulsion layer. Following exposure and development, a thermoplastic foil is laid over the emulsion layer and bonded in place using an optical quality adhesive.