Patents by Inventor Anne V. Smith

Anne V. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Reducing HTT Expression
    Publication number: 20260234628
    Abstract: Provided herein are methods of administering ISIS 443139 for ameliorating Huntington's disease, reducing HTT RNA, reducing mHTT RNA, reducing HTT protein, or reducing mHTT protein in a human subject in need thereof. In certain instances, methods are useful for ameliorating at least one symptom of Huntington's disease. Such symptoms of Huntington's disease include, but are not limited to, brain atrophy, muscle atrophy, nerve degeneration, uncontrolled movement, difficulty swallowing, difficulty speaking, anxiety and depression.
    Type: Application
    Filed: April 27, 2026
    Publication date: August 13, 2026
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: C. Frank Bennett, Daniel A. Norris, Anne V. Smith, Roger Lane
  • METHODS FOR REDUCING HTT EXPRESSION
    Publication number: 20230108340
    Abstract: Provided herein are methods of administering ISIS 443139 for ameliorating Huntington's disease, reducing HTT RNA, reducing mHTT RNA, reducing HTT protein, or reducing mHTT protein in a human subject in need thereof. In certain instances, methods are useful for ameliorating at least one symptom of Huntington's disease. Such symptoms of Huntington's disease include, but are not limited to, brain atrophy, muscle atrophy, nerve degeneration, uncontrolled movement, difficulty swallowing, difficulty speaking, anxiety and depression.
    Type: Application
    Filed: February 19, 2021
    Publication date: April 6, 2023
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: C. Frank Bennett, Daniel A. Norris, Anne V. Smith, Roger Lane