Abstract: A method is provided for treating a subject for a viral infection. The method includes diagnosing the subject as having a viral infection, and administering a pharmaceutically effective amount of a pharmaceutical composition to the subject. The pharmaceutical composition includes a poly-N-substituted glycine compound of a formula wherein A is a terminal N-alkyl substituted glycine residue; n is an integer; B is selected from the group consisting of NH2, one and two N-substituted glycine residues, and wherein said one and two N-substituted glycine residues have N-substituents which are independently selected from natural ?-amino acid side chain moieties, isomers and carbon homologs thereof; X, Y and Z are independently selected from the group consisting of N-substituted glycine residues, wherein said N-substituents are independently selected from the group consisting of natural ?-amino acid side chain moieties, isomers and carbon homologs thereof, and proline residues.

Abstract: Compositions are provided which feature mixtures of at least a first and second peptoid. The second peptoid has a terminal aliphatic moiety, while the first peptoid lacks a terminal aliphatic moiety. These compositions have various end uses, including the treatment of various cancers and tumors and the treatment of bacterial, fungal, microbial or parasitic infections.

Abstract: A method is provided for performing electromagnetic radiation therapy on a subject. The method comprises providing a device which emits electromagnetic radiation, wherein the electromagnetic radiation includes a first portion that oscillates between at least first and second distinct states, and a second non-oscillatory portion; and illuminating the subject with the electromagnetic radiation.

Abstract: A method is provided for treating a plaque-based arterial occlusion in a carotid artery of a subject. The method includes performing a carotid endarterectomy on the subject; determining the levels in the subject of a plurality of biomarkers Bi?[B1, . . . , Bn], wherein n ?2; and performing light therapy on the subject if any of the plurality of biomarkers Bi has a level xi in excess of a corresponding threshold value ti.

Abstract: A method for treating a subject is provided. The method includes performing surgery on the subject such as, for example, a carotid endarterectomy. Light therapy is administered to the subject as an adjuvant to the surgery.

Abstract: Methods for treating bacterial infections using combination therapy with thiourea or a derivative thereof and an antimicrobial peptoid are disclosed. Treatment may further comprise administration of an antibiotic. The disclosed methods may be used for the treatment of acute and chronic bacterial infections. The antimicrobial peptoid may be a self-assembly peptoid.

Abstract: A method for treating type 2 diabetes (T2D) is provided. The method comprises diagnosing a subject as suffering from T2D or as being pre-diabetic; monitoring the response to glucose stimulation of at least one islet in the pancreas of the subject by quantitatively imaging glucose metabolism in vivo; establishing a target range for the response to glucose stimulation of the at least one islet; and upregulating cathelicidin gene expression in the subject until the monitored response to glucose stimulation is within the target range.

Abstract: Provided herein are compounds, compositions, and methods for treating disorders (e.g., opioid addiction) using compounds disclosed herein, which are selective agonists of the cannabinoid 2 receptor (CB2R).

Abstract: A method is provided for treating a surface containing a plurality of functional groups. The method includes reacting the plurality of functional groups with a linking group, thereby creating a surface containing a plurality of linking groups; and binding a first peptoid to each of the plurality of linking groups, thereby obtaining a first treated surface.

Abstract: A method is provided for treating a subject suffering from a chronic infection that involves the brain. The chronic infection may range from those causing only mild cognitive impairment, to those present in individuals who have been diagnosed with Alzheimer's Disease. The method includes forming a composition containing (a) an anti-infective peptoid, and (b) a blood-brain barrier (BBB) manipulator that enhances the ability of the anti-infective peptoid to cross the BBB; and administering a therapeutic amount of the composition to a subject in need thereof.

Abstract: A method for treating a subject suffering from a disease is provided. The method includes diagnosing the subject as suffering from a disease; upregulating the cathelicidin gene CAMP in the subject; and administering to the subject at least one treatment for the disease.

Abstract: In one aspect, a method is provided for performing light therapy on a subject. The method comprises providing a device which emits electromagnetic radiation that oscillates between at least first and second distinct polarization states; and illuminating the subject with the emitted electromagnetic radiation. In another aspect, a fixture is provided which comprises a first source of electromagnetic radiation which emits electromagnetic radiation in a first polarization state; a second source of electromagnetic radiation which emits electromagnetic radiation in a second polarization state which is distinct from said first polarization state; and an oscillator which oscillates electromagnetic radiation output by the fixture between at least said first and second polarization states.

Abstract: Systems and methodologies are provided for performing brainwave entrainment on a subject. An exemplary embodiment of these methodologies includes providing a signal source selected from the group consisting of audio signal sources and video signal sources; and using the signal source to apply to the subject, or to induce the formation of in the subject, at least one nested waveform selected from the group consisting of audio waves and electromagnetic waves.

Abstract: A method is provided for treating a recipient with a biological product obtained from at least one donor that may be the same as, or different from, the recipient. The method includes identifying a targeted level of gene expression of a first gene in a biological product to be transferred from at least one donor to a recipient; treating the at least one donor to achieve the targeted level of gene expression of the first gene in the biological product; and transferring the biological product from the at least one donor to the recipient.

Abstract: A method is provided for treating a subject. The method comprises diagnosing the subject as suffering from a condition arising from the presence in the subject of a causative agent; and administering to the subject a pharmaceutically effective amount of a substance having (a) a hydrophobic, helical region, (b) an N-terminal region that includes at least one proline residue, (c) a first linking moiety that links the hydrophobic helical region to the N-terminal region, said linking moiety being equipped with at least one lysine-like side chain, (d) a binding moiety which binds to the causative agent, and (e) a second linking moiety that links the binding moiety to the N-terminal region.

Abstract: A method is provided for treating a recipient with a biological product obtained from at least one donor that may be the same as, or different from, the recipient. The method includes identifying a targeted level of gene expression of a first gene in a biological product to be transferred from at least one donor to a recipient; treating the at least one donor to achieve the targeted level of gene expression of the first gene in the biological product; and transferring the biological product from the at least one donor to the recipient.

Abstract: A contraceptive device is provided which includes a (preferably elastomeric) surface; and a lubricant applied to the surface. The lubricant includes (a) a lubricious medium, and (b) a pharmaceutically effective amount of a peptoid disposed in said lubricious medium. The antimicrobial peptoid may impart protection against some common sexually transmitted diseases, while also imparting spermicidal activity to the lubricious medium and contraceptive device.

Abstract: A method for treating a subject suffering from cancer is provided. The method includes diagnosing the subject as suffering from cancer; obtaining Natural Killer (NK) white blood cells; upregulating the cathelicidin gene CAMP in the subject; and infusing the NK cells into the body of the subject.

Abstract: A polytherapy of orally available compounds is disclosed that synergistically modulates and induces the expression of the cathelicidin gene (CAMP), which encodes the host defense peptide LL-37. By providing a number of different CAMP-inducing compounds together at the same time, stronger gene induction is achieved than with just one or two compounds, because the mechanism of induction broadens. Induction also may vary in different pas of the body depending on which compounds are used, and at what levels. We show for the first time that the polytherapy can induce cathelicidin expression in the brain, which may help to treat or prevent Alzheimer's Disease Systemic cathelicidin gene induction may help treat numerous other conditions including Type 2 Diabetes/Metabolic Syndrome, or chronic bacterial, viral, or fungal infections associated with increased cancer risk or neurodegeneration.

Abstract: A method is provided for performing electromagnetic radiation therapy on a subject. The method comprises providing a device which emits electromagnetic radiation, wherein the electromagnetic radiation includes a first portion that oscillates between at least first and second distinct states, and a second non-oscillatory portion; and illuminating the subject with the electromagnetic radiation.