Patents by Inventor Annemie BIESEMANS

Annemie BIESEMANS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPORES WITH INTERNAL PROTEIN ADAPTORS
    Publication number: 20220091096
    Abstract: A method for detecting an analyte in a sample includes the steps of obtaining a nanopore sensor comprising a nanopore and a protein adaptor internalized in the lumen of the nanopore, adding a sample comprising an analyte to the cis side or the trans side of the nanopore, and measuring conductance across the nanopore. A change in conductance after adding the sample indicates the analyte is present in the sample and has bound to the protein adaptor. Nanopore sensors comprise a nanopore and a protein adaptor internalized in the lumen of the nanopore. The protein adaptor is a functional enzyme or ligand-binding protein.
    Type: Application
    Filed: September 28, 2021
    Publication date: March 24, 2022
    Applicants: Katholieke Universiteit Leuven, Rijksuniversiteit Groningen
    Inventors: Giovanni Maglia, Mikhael Soskine, Annemie Biesemans, Veerle van Meervelt, Bert Poolman, Gea Schuurman-Wolters
  • Nanopores with internal protein adaptors
    Patent number: 11169138
    Abstract: A method for detecting an analyte in a sample includes the steps of obtaining a nanopore sensor comprising a nanopore and a protein adaptor internalized in the lumen of the nanopore, adding a sample comprising an analyte to the cis side or the trans side of the nanopore, and measuring conductance across the nanopore. A change in conductance after adding the sample indicates the analyte is present in the sample and has bound to the protein adaptor. Nanopore sensors comprise a nanopore and a protein adaptor internalized in the lumen of the nanopore. The protein adaptor is a functional enzyme or ligand-binding protein.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: November 9, 2021
    Assignees: Katholieke Universiteit Leuven, Rijksuniversiteit Groningen
    Inventors: Giovanni Maglia, Mikhael Soskine, Annemie Biesemans, Veerle Van Meervelt, Bert Poolman, Gea Schuurman-Wolters
  • NANOPORES WITH INTERNAL PROTEIN ADAPTORS
    Publication number: 20180209952
    Abstract: A method for detecting an analyte in a sample includes the steps of obtaining a nanopore sensor comprising a nanopore and a protein adaptor internalized in the lumen of the nanopore, adding a sample comprising an analyte to the cis side or the trans side of the nanopore, and measuring conductance across the nanopore. A change in conductance after adding the sample indicates the analyte is present in the sample and has bound to the protein adaptor. Nanopore sensors comprise a nanopore and a protein adaptor internalized in the lumen of the nanopore. The protein adaptor is a functional enzyme or ligand-binding protein.
    Type: Application
    Filed: April 14, 2016
    Publication date: July 26, 2018
    Inventors: Giovanni MAGLIA, Mikhael SOSKINE, Annemie BIESEMANS, Veerle VAN MEERVELT, Bert POOLMAN, Gea SCHUURMAN-WOLTERS