Patents by Inventor Annette Deufel

Annette Deufel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable Taq polymerase fragment
    Patent number: 7972830
    Abstract: It was found that a fragment of native Thermus aquaticus DNA polymerase (TaqWT) lacking 288 N-terminal amino acids (Taq?288) possesses an increased thermostability over TaqWT, Taq?279, and Taq?289. The present invention therefore provides Taq?288, recombinant expression vectors encoding the same or derivatives thereof, as well as purification protocols for Taq?288. The invention also encompasses kits containing Taq?288 as well as the use of Taq?288 and kits containing Taq?288. In addition, the invention encompasses methods for the sequencing a nucleic acid template and methods for amplifying a target nucleic acid.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: July 5, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Thomas Meier, Waltraud Ankenbauer, Annette Deufel, Dieter Heindl, Gisela Betzl, Rainer Schmuck, Bernd Schneidinger, Jessica Strey
  • Thermostable Taq polymerase fragment
    Publication number: 20050037412
    Abstract: It was found that a fragment of native Thermus aquaticus DNA polymerase (TaqWT) lacking 288 N-terminal amino acids (Taq?288) possesses an increased thermostability over TaqWT, Taq?279, and Taq?289. The present invention therefore provides Taq?288, recombinant expression vectors encoding the same or derivatives thereof, as well as purification protocols for Taq?288. The invention also encompasses kits containing Taq?288 as well as the use of Taq?288 and kits containing Taq?288. In addition, the invention encompasses methods for the sequencing a nucleic acid template and methods for amplifying a target nucleic acid.
    Type: Application
    Filed: August 12, 2004
    Publication date: February 17, 2005
    Inventors: Thomas Meier, Waltraud Ankenbauer, Annette Deufel, Dieter Heindl, Gisela Betzl, Rainer Schmuck, Bernd Schneidinger, Jessica Strey