Patents by Inventor Annette Gilchrist

Annette Gilchrist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating atrial or ventricular arrhythmias
    Patent number: 8193151
    Abstract: The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: June 5, 2012
    Assignee: Northwestern University
    Inventors: Rishi Arora, Alan Kadish, Annette Gilchrist
  • COMPOSITIONS AND METHODS FOR TREATING ATRIAL FIBRILLATION
    Publication number: 20090281019
    Abstract: The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
    Type: Application
    Filed: April 27, 2009
    Publication date: November 12, 2009
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Rishi Arora, Alan Kadish, Annette Gilchrist
  • G protein coupled receptor signaling modulation
    Publication number: 20080280308
    Abstract: This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.
    Type: Application
    Filed: November 6, 2007
    Publication date: November 13, 2008
    Applicant: Caden Biosciences
    Inventors: Annette Gilchrist, Heidi M. Hamm
  • Method for identifying modulators of G protein coupled receptor signaling
    Patent number: 7294472
    Abstract: This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: November 13, 2007
    Assignee: Caden Biosciences
    Inventors: Annette Gilchrist, Heidi M. Hamm
  • Method for identifying inhibitors of G protein coupled receptor signaling
    Publication number: 20070231830
    Abstract: This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed.
    Type: Application
    Filed: April 20, 2007
    Publication date: October 4, 2007
    Applicant: Caden Biosciences
    Inventors: Annette Gilchrist, Heidi Hamm
  • Method for identifying inhibitors of G protein coupled receptor signaling
    Patent number: 7208279
    Abstract: This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: April 24, 2007
    Assignee: Caden Biosciences, Inc.
    Inventors: Annette Gilchrist, Heidi M. Hamm
  • Method for identifying modulators of G protein coupled receptor signaling
    Publication number: 20070077597
    Abstract: This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.
    Type: Application
    Filed: October 2, 2006
    Publication date: April 5, 2007
    Applicant: cue BIOtech, Inc.
    Inventors: Annette Gilchrist, Heidi Hamm
  • Method for identifying modulators of G protein coupled receptor signaling
    Publication number: 20040018558
    Abstract: This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assays, methods of treatment and other methods developed in conjunction with these methods also are disclosed.
    Type: Application
    Filed: April 11, 2003
    Publication date: January 29, 2004
    Inventors: Annette Gilchrist, Heidi M. Hamm
  • Inhibitors of G protein-mediated signaling, methods of making them, and uses thereof
    Publication number: 20030162258
    Abstract: The invention provides compositions and methods useful for blocking G protein-mediated signaling events. Compositions provided by the invention relate to carboxy terminal G&agr; peptides, and minigenes which encode such peptides. The invention provides methods of making the minigenes, and methods of using either of the minigenes and the G&agr; carboxy terminal peptides encoded thereby, to block G protein-mediated signaling events. The invention also provides methods of using either of the minigenes and the G&agr; carboxy terminal peptides encoded thereby for the identification of unknown interactions between G proteins and G protein coupled receptors, and for the treatment of pathological disorders associated with G protein-mediated signaling events.
    Type: Application
    Filed: February 24, 2003
    Publication date: August 28, 2003
    Applicant: Northwestern University
    Inventors: Heidi E. Hamm, Annette Gilchrist
  • Method for identifying inhibitors of G protein coupled receptor signaling
    Publication number: 20030096297
    Abstract: This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed.
    Type: Application
    Filed: May 11, 2001
    Publication date: May 22, 2003
    Inventors: Annette Gilchrist, Heidi M. Hamm
  • Inhibitors of G protein-mediated signaling, methods of making them, and uses thereof
    Patent number: 6559128
    Abstract: The invention provides compositions and methods useful for blocking G protein-mediated signaling events. Compositions provided by the invention relate to carboxy terminal G&agr; peptides, and minigenes which encode such peptides. The invention provides methods of making the minigenes, and methods of using either of the minigenes and the G&agr; carboxy terminal peptides encoded thereby, to block G protein-mediated signaling events. The invention also provides methods of using either of the minigenes and the G&agr; carboxy terminal peptides encoded thereby for the identification of unknown interactions between G proteins and G protein coupled receptors, and for the treatment of pathological disorders associated with G protein-mediated signaling events.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: May 6, 2003
    Assignee: Northwestern University
    Inventors: Heidi E. Hamm, Annette Gilchrist