Patents by Inventor Annette Khaled

Annette Khaled has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHAPERONIN-CONTAINING TCP-1 INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20240141352
    Abstract: Disclosed herein are compositions and uses thereof for treating cancers.
    Type: Application
    Filed: March 7, 2022
    Publication date: May 2, 2024
    Inventor: Annette KHALED
  • CORONAL PROTEIN-COATED NANOPARTICLES AND USES THEREOF
    Publication number: 20240122867
    Abstract: Disclosed are nanoparticle compositions and methods for treating cancer. Further, hyperbranched polyester (HBPE) nanoparticle that comprise one or more coronal proteins are disclosed herein.
    Type: Application
    Filed: February 14, 2022
    Publication date: April 18, 2024
    Inventors: Annette KHALED, Lei ZHAI, Kai MCKINSTRY, Daniel NIERENBERG
  • METHODS AND COMPOSITIONS COMPRISING A CT20 PEPTIDE
    Publication number: 20230035748
    Abstract: Disclosed herein are compositions comprising a CT20 peptide and methods of using the disclosed compositions to treat cancers expressing chaperonin containing TCP (CCT).
    Type: Application
    Filed: March 5, 2022
    Publication date: February 2, 2023
    Inventor: Annette Khaled
  • METHODS AND COMPOSITIONS COMPRISING A C-TERMINAL BAX PEPTIDE
    Publication number: 20220175877
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Application
    Filed: November 22, 2021
    Publication date: June 9, 2022
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • METHOD AND COMPOSITIONS COMPRISING A CT20 PEPTIDE
    Publication number: 20220096593
    Abstract: Disclosed herein are compositions comprising a CT20 peptide and methods of using the disclosed compositions to treat cancers expressing chaperonin containing TCP (CCT).
    Type: Application
    Filed: September 27, 2021
    Publication date: March 31, 2022
    Inventors: Annette Khaled, Jesus Manuel Perez, Rania Bassiouni
  • Methods and compositions comprising a C-terminal Bax peptide
    Patent number: 11179436
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: November 23, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • Method and compositions comprising a CT20 peptide
    Patent number: 11129868
    Abstract: Disclosed herein are compositions comprising a CT20 peptide and methods of using the disclosed compositions to treat cancers expressing chaperonin containing TCP (CCT).
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: September 28, 2021
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Annette Khaled, Jesus Manuel Perez, Rania Bassiouni
  • METHODS AND COMPOSITIONS FOR THERANOSTIC NANOPARTICLES
    Publication number: 20210228733
    Abstract: Disclosed are compositions and methods for identifying a solid tumor cell target. Compositions and methods for treating prostate cancer are also disclosed. Further, cancer therapeutic compositions comprising CT20p are disclosed. Nanoparticles that are conjugated with a targeting ligand that is a substrate for a solid tumor-specific cell protein are disclosed.
    Type: Application
    Filed: April 12, 2021
    Publication date: July 29, 2021
    Applicants: University of Central Florida Research Foundation, Inc., Sanford Burnham Prebys Medical Discovery Institute at Lake Nona, Memorial Sloan Kettering Cancer Center
    Inventors: Annette Khaled, Jesus Manuel Perez Figueroa, Santimukul Santra, Charalambos Kaittanis, Oscar Santiesteban, Jan Grimm, Hampton Sessions
  • Methods and compositions for theranostic nanoparticles
    Patent number: 10973925
    Abstract: Disclosed are compositions and methods for identifying a solid tumor cell target. Compositions and methods for treating prostate cancer are also disclosed. Further, cancer therapeutic compositions comprising CT20p are disclosed. Nanoparticles that are conjugated with a targeting ligand that is a substrate for a solid tumor-specific cell protein are disclosed.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: April 13, 2021
    Assignees: University of Central Florida Research Foundation Inc., Sanford Burnham Prebys Medical Discovery Institute at Lake Nona, Memorial Sloan Kettering Cancer Center
    Inventors: Annette Khaled, Jesus Manuel Perez Figueroa, Santimukul Santra, Charalambos Kaittanis, Oscar Santiesteban, Jan Grimm, Hampton Sessions
  • METHODS AND COMPOSITIONS COMPRISING A C-TERMINAL BAX PEPTIDE
    Publication number: 20190183965
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • Methods and compositions comprising a C-terminal Bax peptide
    Patent number: 10159706
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: December 25, 2018
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • METHODS AND COMPOSITIONS FOR THERANOSTIC NANOPARTICLES
    Publication number: 20180126002
    Abstract: Disclosed are compositions and methods for identifying a solid tumor cell target. Compositions and methods for treating prostate cancer are also disclosed. Further, cancer therapeutic compositions comprising CT20p are disclosed. Nanoparticles that are conjugated with a targeting ligand that is a substrate for a solid tumor-specific cell protein are disclosed.
    Type: Application
    Filed: April 28, 2016
    Publication date: May 10, 2018
    Inventors: Annette Khaled, Jesus Manuel Perez Figueroa, Santimukul Santra, Charalambos Kaittanis, Oscar Santiesteban, Jan Grimm, Hampton Sessions
  • METHOD AND COMPOSITIONS COMPRISING A CT20 PEPTIDE
    Publication number: 20170165318
    Abstract: Disclosed herein are compositions comprising a CT20 peptide and methods of using the disclosed compositions to treat cancers expressing chaperonin containing TCP (CCT).
    Type: Application
    Filed: July 9, 2015
    Publication date: June 15, 2017
    Inventors: Annette Khaled, Jesus Manuel Perez, Rania Bassiouni
  • Compositions and methods for purifying Bax
    Patent number: 9403888
    Abstract: Disclosed are compositions and methods for purifying a Bax protein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: August 2, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Annette Khaled
  • Compositions comprising IL-7 receptor ligands
    Patent number: 9266937
    Abstract: Disclosed herein are novel proteins that have reduced binding to the interleukin-7 receptor, compositions containing such proteins, and methods of using the same.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: February 23, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Annette Khaled
  • METHODS AND COMPOSITIONS COMPRISING A C-TERMINAL BAX PEPTIDE
    Publication number: 20150359841
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Application
    Filed: May 20, 2015
    Publication date: December 17, 2015
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • Methods and compositions comprising a C-terminal Bax peptide
    Patent number: 9040662
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: May 26, 2015
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • COMPOSITIONS AND METHODS FOR PURIFYING BAX
    Publication number: 20140349344
    Abstract: Disclosed are compositions and methods for purifying a Bax protein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 27, 2014
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventor: Annette Khaled
  • Methods and Compositions Comprising a C-Terminal Bax Peptide
    Publication number: 20140255299
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Application
    Filed: August 24, 2012
    Publication date: September 11, 2014
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • Methods and Compositions Comprising IL-7 Receptor Ligands
    Publication number: 20130330296
    Abstract: Disclosed herein are novel proteins that have reduced binding to the interleukin-7 receptor, compositions containing such proteins, and methods of using the same.
    Type: Application
    Filed: December 9, 2011
    Publication date: December 12, 2013
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventor: Annette Khaled