Patents by Inventor Annette Shadiack

Annette Shadiack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic peptides for treatment of cachexia
    Publication number: 20060014676
    Abstract: A highly selective melanocortin-4 receptor antagonist cyclic peptide of the formula where R1, R2, R3, R4a, R4b, R5, R6, R7, x, y and z are as defined in the specification, and a method of treating body weight disorders, including cachexia, sarcopenia and wasting syndrome or disease, and treating inflammation and immune disorders.
    Type: Application
    Filed: July 5, 2005
    Publication date: January 19, 2006
    Applicant: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Ramesh Rajpurohit, Annette Shadiack, Yi-Qun Shi, Kevin Burris
  • Cyclic peptides for treatment of cachexia
    Publication number: 20060014194
    Abstract: A highly selective melanocortin-4 receptor antagonist cyclic hexapeptide of the formula where R1, R2, R3a, R3b, R4, R5, x, y and z are as defined in the specification, and a method of treating body weight disorders, including cachexia, sarcopenia and wasting syndrome or disease, and treating inflammation and immune disorders.
    Type: Application
    Filed: July 5, 2005
    Publication date: January 19, 2006
    Applicant: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Ramesh Rajpurohit, Annette Shadiack, Yi-Qun Shi, Kevin Burris
  • Multiple agent therapy for sexual dysfunction
    Publication number: 20050222014
    Abstract: Multiple agent therapy for treatment of sexual dysfunction, including male erectile dysfunction, with sequential administration a type V phosphodiesterase inhibitor (PDE-5), such as sildenafil, preferably wherein the PDE-5 inhibitor is administered by oral dose means, and a melanocortin 3 and/or 4 receptor agonist, such as Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH (PT-141) preferably wherein the PT-141 is formulated for and administered by intranasal means, and further preferably wherein the PDE-5 inhibitor is administered prior to PT-141.
    Type: Application
    Filed: May 26, 2005
    Publication date: October 6, 2005
    Applicant: Palatin Technologies, Inc.
    Inventors: Lisa Diamond, Dennis Earle, Annette Shadiack, Shubh Sharma, Carl Spana
  • Metallopeptide compositions for treatment of sexual dysfunction
    Publication number: 20050164914
    Abstract: Metallopeptide compositions are provided for treatment of sexual dysfunction in mammals, including male sexual dysfunction, such as erectile dysfunction, and female sexual dysfunction. The metallopeptides include at least one, and preferably two, aromatic amino acid side chain moieties, and are further characterized in that the metallopeptides preferably do not bind or significantly bind to a melanocortin receptor.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 28, 2005
    Applicant: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Wei Yang, Ramesh Rajpurohit
  • Naphthalene-containing melanocortin receptor-specific small molecule
    Publication number: 20050130988
    Abstract: A method of modulating energy homeostasis in a mammal without eliciting a sexual response by administration of a therapeutically effective amount of a pharmaceutical composition including a melanocortin receptor compound of the formula: where R1 is a bond or a linker unit including from one to six backbone atoms and an unsubstituted naphthalene group, and L, R2, R3 and Rx are as defined in the specification.
    Type: Application
    Filed: January 14, 2005
    Publication date: June 16, 2005
    Applicant: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Yi- Qun Shi, Zhijun Wu, Ramesh Rajpurohit, Kevin Burris, Papireddy Purma
  • Peptide compositions for treatment of sexual dysfunction
    Publication number: 20050124553
    Abstract: A peptide of the structural formula: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, m and n are as defined. Further provided are methods for treatment of sexual dysfunction, including erectile dysfunction and female sexual dysfunction, and combination drugs and method of use thereof, including a peptide of the invention and one or more second sexual dysfunction pharmaceutical agents.
    Type: Application
    Filed: January 7, 2005
    Publication date: June 9, 2005
    Applicant: Palatine Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Ramesh Rajpurohit, Wei Yang
  • Composition and methods for treatment of sexual dysfunction
    Publication number: 20050037951
    Abstract: Compositions and methods are provided for treatment of sexual dysfunction in mammals, including male sexual dysfunction, such as erectile dysfunction, and female sexual dysfunction, wherein pharmaceutically sufficient quantities of a linear or cyclic peptide with a carboxyl terminus —OH group or pharmaceutically acceptable salt thereof and a core His-Phe-Arg-Trp (SEQ ID NO:1) or His-D-Phe-Arg-Trp sequence are administered. Methods of administration include injection, oral, nasal and mucosal administration.
    Type: Application
    Filed: September 20, 2004
    Publication date: February 17, 2005
    Applicant: Palatin Technologies, Inc.
    Inventors: Christine Blood, Annette Shadiack, Guy Herbert, Joanna Bernstein
  • Linear and cyclic melanocortin receptor-specific peptides
    Publication number: 20050038230
    Abstract: Linear and cyclic peptides are provided specific to one or melanocortin receptors, and which exhibit agonist, antagonist, or mixed agonist-antagonist activity.
    Type: Application
    Filed: January 12, 2004
    Publication date: February 17, 2005
    Applicant: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Wei Yang, Ramesh Rajpurohit