Patents by Inventor Anni Warri

Anni Warri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REVERSAL OF HIGH BREAST CANCER RISK IN MAMMALS EXPOSED TO ESTROGENIC CHEMICALS IN UTERO BY ADULT EXPOSURE TO HDAC AND DNMT INHIBITORS
    Publication number: 20130324543
    Abstract: Methods of reducing breast cancer risk in an individual exposed in utero to an elevated estrogenic environment, where the individuals are identified by obtaining a measurement of at least one of: (a) DNMT1 expression; (b) methylation of normally unmethylated CpG islands of tumor suppressor genes; and (c) polycomb target genes, in cells obtained from the individual and comparing the measurement to a statistical level of a population not exposed in utero to an elevated estrogenic environment. Methods of reducing breast cancer risk in such an individual can be reduced by administering at least one DNA methyltransferase (DNMT) and/or histone deacetylase (HDAC) inhibitor. The administration of these inhibitors may be part of a treatment regime which may include the administration of at least one anti-cancer agent.
    Type: Application
    Filed: April 5, 2013
    Publication date: December 5, 2013
    Applicant: Georgetown University
    Inventors: Leena Hilakivi-Clarke, Anni Warri, Dominic Kim
  • Food product comprising hydroxymatairesinol
    Patent number: 7005447
    Abstract: A food product containing an effective amount of an active agent which is hydroxymatairesinol, a geometric isomer or stereoisomer thereof, or an acceptable salt thereof, or a mixture thereof, where the food product is selected from the group consisting of a nutritional supplement and a nutrient. The food product can increase the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on the administration of hydroxymatairesinol to the person.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: February 28, 2006
    Assignee: Hormos Nutraceutical Oy Ltd.
    Inventors: Markku Ahotupa, Christer Eckerman, Lauri Kangas, Sari Mäkelä, Niina Saarinen, Risto Santti, Anni Wärri
  • Prevention of cancers, non-cancer, hormone dependent diseases and cardiovascular diseases by use of hydroxymatairesinol, and a pharmaceutical preparation, food additive and food product comprising hydroxymatairesinol
    Publication number: 20040048804
    Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
    Type: Application
    Filed: August 13, 2003
    Publication date: March 11, 2004
    Inventors: Markku Ahotupa, Christer Eckerman, Lauri Kangas, Sari Makela, Niina Saarinen, Risto Santti, Anni Warri
  • Food additive or product or a pharmaceutical preparation, comprising hydroxymatairesinol
    Patent number: 6689809
    Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: February 10, 2004
    Assignee: Hormos Nutraceutical Oy Ltd.
    Inventors: Markku Ahotupa, Christer Eckerman, Lauri Kangas, Sari Mäkelä, Niina Saarinen, Risto Santti, Anni Wärri
  • Remedy for autoimmune diseases
    Patent number: 6458848
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: October 1, 2002
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • USE OF HYDROXYMATAIRESINOL FOR PREVENTION OF CANCERS, NON-CANCER, HORMONE DEPENDENT DISEASES AND CARDIOVASCULAR DISEASES BY HYDROXYMATAIRESINOL, AND A PHARMACEUTICAL PREPARATION, FOOD ADDITIVE AND FOOD PRODUCT COMPRISING HYDROXYMATAIRESINOL
    Patent number: 6451849
    Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: September 17, 2002
    Assignee: Hormos Nutraceutical Oy Ltd.
    Inventors: Markku Ahotupa, Chester Eckerman, Lauri Kangas, Sari Mäkelä, Niina Saarinen, Risto Santti, Anni Wärri
  • Remedy for autoimmune diseases
    Publication number: 20020107231
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Application
    Filed: January 10, 2002
    Publication date: August 8, 2002
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Prevention of cancers, non-cancer, hormone dependent diseases and cardiovascular diseases by use of hydroxymatairesinol, and a pharmaceutical preparation, food additive and food product comprising hydroxymatairesinol
    Publication number: 20020061854
    Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
    Type: Application
    Filed: October 10, 2001
    Publication date: May 23, 2002
    Inventors: Markku Ahotupa, Christer Eckerman, Lauri Kangas, Sari Makela, Niina Saarinen, Risto Santti, Anni Warri
  • Remedy for autoimmune diseases
    Patent number: 6387958
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: May 14, 2002
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itöh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 6355688
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: March 12, 2002
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Use of hydroxymatairesinol for prevention of cancers, non-cancer, hormone dependent diseases and cardiovascular diseases by hydroxymatairesinol, and a pharmaceutical preparation, food additive and food product comprising hydroxymatairesinol
    Publication number: 20010016590
    Abstract: This invention relates to methods for prevention of cancers, certain non-cancer, hormone dependent diseases and/or cardiovascular diseases in a person, based on administering of hydroxymatairesinol to said person. The invention also concerns a method for increasing the level of enterolactone or another metabolite of hydroxymatairesinol in a person's serum thereby causing prevention of a cancer or a certain non-cancer, hormone dependent disease in a person, based on administering of hydroxymatairesinol to said person. Furthermore, this invention relates to pharmaceutical preparations, food additives and food products comprising hydroxymatairesinol.
    Type: Application
    Filed: April 11, 2001
    Publication date: August 23, 2001
    Inventors: Markku Ahotupa, Christer Eckerman, Lauri Kangas, Sari Makela, Niina Saarinen, Risto Santti, Anni Warri
  • Remedy for autoimmune diseases
    Patent number: 6184253
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: February 6, 2001
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 5886049
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: March 23, 1999
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Syndecan stimulation of cellular differentiation
    Patent number: 5726058
    Abstract: Methods are provided for altering levels of syndecan within a cell. The methods include enhancing syndecan expression via administration of growth factors, preventing suppression of syndecan expression via administration of anti-steroid agents, and altering syndecan biochemistry within the cell. The methods are used to induce or maintain cellular differentiation, and to decrease the growth of malignant cells. Application of the methods to the treatment of patients, including humans, is provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 10, 1998
    Inventors: Markku Jalkanen, Leena Alanen-Kurki, Petri Auvinen, Panu Jaakkola, Sirpa Leppa, Markku Mali, Tapani Vihinen, Anni Warri