Patents by Inventor Annick Arbellot De Vacqueur

Annick Arbellot De Vacqueur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazole derivatives as fructose-1,6-bisphosphatase inhibitors and pharmaceutical compositions containing them
    Patent number: 8673955
    Abstract: Imidazole derivatives of formula (I): wherein R1, R2a, R2b, A, V and W are as defined in the description, as inhibitors of fructose-1,6-bisphosphatase, their preparation process and their use in the prevention or treatment of diabetes, and other diseases where the inhibition of gluconeogenesis, control of blood glucose levels, reduction in glycogen stores, or reduction in insulin levels is beneficial and diseases related to the insulin resistance syndrome.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: March 18, 2014
    Assignee: Merck Patent GmbH
    Inventors: Denis Carniato, Gérard Moinet, Gérard Botton, Annick Arbellot De Vacqueur, Annick Audet
  • Imidazolecarboxamide derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same
    Patent number: 8362057
    Abstract: The invention relates to the compounds of the general formula (I): in which A, D, R, R1 and X are as defined in the description, to a process for the preparation thereof and to the therapeutic use thereof in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: January 29, 2013
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Gérard Moinet, Gérard Botton, Annick Arbellot de Vacqueur
  • Benzimidazoledihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same
    Patent number: 8232272
    Abstract: The present invention relates to novel benzimidazole-dihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, to processes for the preparation thereof and to the use thereof in therapy, especially for the treatment of diabetes.
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: July 31, 2012
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Gerard Botton, Caroline Leriche, Annick Arbellot de Vacqueur, Annick Audet, Johannes Gleitz
  • NOVEL BENZIMIDAZOLEDIHYDROTHIADIAZINONE DERIVATIVES AS FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
    Publication number: 20100286129
    Abstract: The present invention relates to novel benzimidazole-dihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, to processes for the preparation thereof and to the use thereof in therapy, especially for the treatment of diabetes.
    Type: Application
    Filed: October 13, 2008
    Publication date: November 11, 2010
    Inventors: Gerard Botton, Caroline Leriche, Annick Arbellot De Vacqueur, Annick Audet, Johannes Gleitz
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes
    Patent number: 7727977
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: June 1, 2010
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Gérard Moinet, Dominique Mariais, Catherine Kargar, Micheline Kergoat
  • Imidazole Derivatives as Fructose-1,6-Bisphosphatase Inhibitors and Pharmaceutical Compositions Containing Them
    Publication number: 20080312299
    Abstract: Imidazole derivatives of formula (I) wherein R1, R2a, R2b, A, V and W are as defined in the description, as inhibitors of fructose-1,6-bisphosphatase, their preparation process and their use in the prevention or treatment of diabetes, and other diseases where the inhibition of gluconeogenesis, control of blood glucose levels, reduction in glycogen stores, or reduction in insulin levels is beneficial and diseases related to the insulin resistance syndrome.
    Type: Application
    Filed: July 19, 2006
    Publication date: December 18, 2008
    Inventors: Denis Carniato, Gerard Moinet, Gerard Botton, Annick Arbellot De Vacqueur, Annick Audet
  • Novel Imidazolecarboxamide Derivatives as Fructose-1,6-Bisphosphatase Inhibitors, and Pharmaceutical Compositions Comprising Same
    Publication number: 20080207720
    Abstract: The invention relates to the compounds of the general formula (I): in which A, D, R, R1 and X are as defined in the description, to a process for the preparation thereof and to the therapeutic use thereof in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Application
    Filed: July 7, 2006
    Publication date: August 28, 2008
    Inventors: Gerard Moinet, Gerard Botton, Annick Arbellot de Vacqueur
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes
    Publication number: 20060142358
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 29, 2006
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes by increasing the number of islets of langerhans cells
    Publication number: 20060052456
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase, for the preparation of a medica ment for increasing the number of islets of Langerhans cells, which is intended especially for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: March 9, 2006
    Applicant: MERCK PATENT GMBH
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar