Patents by Inventor Annie George
Annie George has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12116119Abstract: A rotary wing aircraft includes a single main rotor hub configured to receive a rotor blade. The rotor blade includes a blade root, a blade tip, and a blade body. The blade body includes a leading edge and a trailing edge and defines a feathering axis. The leading edge and the trailing edge each include a first portion and a second portion that extend toward a first direction and a second portion, respectively. At a given radial location along the feathering axis, a local twist angle changes from a positive value to a negative value, a chord length decreases in value, a distance between the trailing edge and the feathering axis decreases in value, and the first portion of the leading edge extends toward the first direction. The rotor blade assembly also includes a trailing edge assembly having a trailing edge flap configured to be selectively deployed by an actuator.Type: GrantFiled: March 28, 2022Date of Patent: October 15, 2024Assignee: LOCKHEED MARTIN CORPORATIONInventors: Byung-Young Min, Vera Klimchenko, Annie Gao, Alexander F. Dunn, Claude George Matalanis, Brian Ernest Wake
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Patent number: 11166998Abstract: A method for stimulating or enhancing the immune system with a composition that includes a Eurycoma longifolia aqueous extract. Also provided is a method for reducing the risk of infectious disease by administering the composition. Further disclosed is a method for treating an individual with a Eurycoma longifolia aqueous extract to increase the number of T-cells, improve Scoring of Immunological Vigor, lower immunological age, reduce fatigue, or alleviate or reduce stress.Type: GrantFiled: December 15, 2017Date of Patent: November 9, 2021Assignee: Biotropics Malaysia BerhadInventors: Annie George, Yuuki Kawasaki, Azreena Abas
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Patent number: 11058737Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.Type: GrantFiled: October 15, 2019Date of Patent: July 13, 2021Assignee: BIOTROPICS MALAYSIA BERHADInventors: Tengku Shahrir Tengku Adnan, Annie George, Sasikala M. Chinnappan
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Publication number: 20200129573Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.Type: ApplicationFiled: October 15, 2019Publication date: April 30, 2020Inventors: Tengku Shahrir TENGKU ADNAN, Annie GEORGE, Sasikala M. CHINNAPPAN
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Publication number: 20180153950Abstract: A method for stimulating or enhancing the immune system with a composition that includes a Eurycoma longifolia aqueous extract. Also provided is a method for reducing the risk of infectious disease by administering the composition. Further disclosed is a method for treating an individual with a Eurycoma longifolia aqueous extract to increase the number of T-cells, improve Scoring of Immunological Vigor, lower immunological age, reduce fatigue, or alleviate or reduce stress.Type: ApplicationFiled: December 15, 2017Publication date: June 7, 2018Inventors: Annie George, Yuuki Kawasaki, Azreena Abas
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Patent number: 9877993Abstract: The present invention relates to a composition containing an extract from the Polygonum minus for cognition and cosmetic purposes. The extract of Polygonum minus includes quercetin-3-glucuronide and quercitrin. Extract of Polygonum minus is provided in an amount effective to reduce oxidative damage. A process for isolation of an active extract from Polygonum minus includes the steps of a) subjecting the Polygonum minus including aerial parts of the plant to solvent extraction preferably with a material solvent ratio of 1:10-20 by percolation at a temperature range of 70-105° C. preferably 80° C. to obtain the extract; and b) filtering the extract obtained from step (a) followed by concentration and drying involving freeze drying, spray drying or vacuum belt drying to obtain therefrom the dry extract powder.Type: GrantFiled: February 26, 2013Date of Patent: January 30, 2018Assignee: BIOTROPICS MALAYSIA BERHADInventors: Annie George V. K. George, Kar Ming Yee
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Patent number: 9497646Abstract: Services and applications running on devices placed in live wireless environments are tested and reported to determine the relative performance of the device under test. Multiple logs collected from the device under test are combined and transmitted to a remote backend system. The backend system stores and analyzes the combined logs to generate reports containing factual and relative performance information regarding the device during the testing period. The nature of the test, the collected log information, and the report format may all be modified according to the criteria of the requestor.Type: GrantFiled: February 18, 2014Date of Patent: November 15, 2016Assignee: AIROMETRIC WIRELESS INC.Inventors: Annie George, Mathew Samuel
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Publication number: 20160206674Abstract: Method for producing an extract or extract formulation of the fruit of Canarium odontophyllum comprising or consisting of the following steps: (i) providing fruit material from Canarium odontophyllum, wherein said fruit material essentially consists of the endocarp of the seeds of Canarium odontophyllum, (i-a) optionally drying the fruit material provided in step (i), (ii) extracting the fruit material provided in step (i) or (i-a) with a mixture essentially consisting or consisting of water and an alcohol having 1 to 3 carbon atoms or consisting water and acetonitrile, (iii) optionally partially or fully removing the alcohol having 1 to 3 carbon atoms of step (ii), and optionally adding an organic solvent of medium polarity to said aqueous residue and extracting the aqueous residue with said organic solvent or a supercritical solvent, such as supercritical carbon dioxide thereby obtaining an enriched extract, (iv) optionally mixing the extract obtained in step (ii) or the enriched extract obtained inType: ApplicationFiled: December 24, 2013Publication date: July 21, 2016Applicant: BIOTROPICS MALAYSIA BHDInventors: MATTHIAS GEHLING, ANNIE GEORGE, SASIKALA M. CHINNAPPAN, MAZRIA HASLINA BINTI MD AKIR
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Publication number: 20160067293Abstract: The present invention discloses the use of a composition comprising an effective amount of an extract of Eurycoma longifolia for the production of a preparation to stimulate and/or enhance the immune system. In a preferred embodiment, the extract comprises active ingredients, which include eurycomanone, protein, polysaccharide and glycosaponin in appropriate amounts. In another preferred embodiment, the extract has an activity selected from the group consisting of: increasing the number of T-cells; improving Scoring of Immunological Vigor (SIV), a comprehensive index of overall immune function; lowering the immunological age, a comprehensible form of immune function based on T-cell number and proliferative activity; reducing fatigue; and alleviating or reducing stress. Also disclosed is a method of for treating an individual to achieve an outcome selected from the group consisting of increasing the number of T-cells, improving SIV (i.e.Type: ApplicationFiled: August 31, 2015Publication date: March 10, 2016Inventors: Annie George, Yuuki Kawasaki, Azreena Abas
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Publication number: 20150320821Abstract: The present invention relates to a composition containing an extract from the Polygonum minus for cognition and cosmetic purposes. The extract of Polygonum minus includes quercetin-3-glucuronide and quercitrin. Extract of Polygonum minus is provided in an amount effective to reduce oxidative damage. A process for isolation of an active extract from Polygonum minus includes the steps of a) subjecting the Polygonum minus including aerial parts of the plant to solvent extraction preferably with a material solvent ratio of 1:10-20 by percolation at a temperature range of 70-105° C. preferably 80° C. to obtain the extract; and b) filtering the extract obtained from step (a) followed by concentration and drying involving freeze drying, spray drying or vacuum belt drying to obtain therefrom the dry extract powder.Type: ApplicationFiled: February 26, 2013Publication date: November 12, 2015Inventors: Annie George V.K. GEORGE, Kar Ming YEE
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Patent number: 8962575Abstract: The use or methods of use of extracts comprising one or more special clerodane compounds against inflammatory (including allergic) diseases or conditions, as well as novel compounds of this type, said clerodane derivatives for use against inflammatory (including allergic) diseases or conditions, pharmaceutical formulations comprising them especially for use against inflammatory disease or conditions, and related embodiments; said extract and/or compound(s) for use in the treatment or in the preparation of a medicament (including a nutraceutical) for the prophylactic and/or therapeutic treatment of said disease or condition, as well as their preparation; pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s) which are useful in said prophylactic and/or therapeutic treatment, and related embodiments.Type: GrantFiled: February 22, 2012Date of Patent: February 24, 2015Assignee: Biotropics Malaysia BerhadInventors: Matthias Gehling, Torsten Grothe, Ernst Roemer, Peter Reinemer, Kathrin Reinhardt, Annie George, Nur Hanisah Mohtar, Noorsyarida Mohd Sapiai
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Publication number: 20150050371Abstract: The present invention primarily relates to the use of certain extract formulations of Rhodamnia cinerea as defined herein as alpha-amylase inhibitors and as actives for the therapeutic (including prophylactic) treatment of a carbohydrate metabolic disorder or of a disease attendant on hyperglycemia, preferably selected from the group consisting of prediabetes, obesity, hyperlipemia, arteriosclerosis, arteriolosclerosis, atherosclerosis, diabetes, postprandial hyperglycemia, and metabolic syndrome. The present invention also relates to corresponding methods. The invention further relates to specific extract formulations obtainable from Rhodamnia cinerea and to compositions, in particular orally consumable compositions, comprising an effective amount of such an extract formulation.Type: ApplicationFiled: March 9, 2012Publication date: February 19, 2015Applicant: BIOTROPICS MALAYSIA BERHADInventors: Matthias Gehling, Bärbel Köpcke, Thomas Küper, Kathrin Reinhardt, Peter Reinemer, Annie George, Sasikala Chinnappan, Mazria Haslina Md Akir
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Publication number: 20140235179Abstract: Services and applications running on devices placed in live wireless environments are tested and reported to determine the relative performance of the device under test. Multiple logs collected from the device under test are combined and transmitted to a remote backend system. The backend system stores and analyzes the combined logs to generate reports containing factual and relative performance information regarding the device during the testing period. The nature of the test, the collected log information, and the report format may all be modified according to the criteria of the requestor.Type: ApplicationFiled: February 18, 2014Publication date: August 21, 2014Applicant: Airometric Wireless Inc.Inventors: Annie GEORGE, Mathew SAMUEL
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Patent number: 8318684Abstract: Seven novel antibiotic substances can be produced by cultivation of a microbial strain which has been isolated from a soil sample and which is designated as Microbispora sp. A 34030 (deposited under an access number FERM BP-10505 in terms of Budapest Treaty). These seven antibiotic substances are named as bispolide A1, bispolide A2, bispolide A3, bispolide B1, bispolide B2a, bispolide B2b and bispolide B3, respectively. These bispolides are each novel compounds which have a chemical structure as collectively represented by the general formula (III) shown below: These bispolides have each a high antibacterial activity against a variety of bacteria, particularly Gram-positive bacteria and their antibiotic-resistant strains, and hence these bispolides each are effective and useful for therapeutically treating bacterial infections of Gram-positive bacteria in humans and animals.Type: GrantFiled: May 15, 2007Date of Patent: November 27, 2012Assignees: Nimura Genetic Solutions Co., Ltd., Forest Research Institute MalaysiaInventors: Keiichi Numata, Noriyuki Okujo, Siew Eim Khor, Lee Li Tan, Annie George, Szu Ting Ng, Chin Jye Tan, Hironobu Iinuma, Yasuo Fukagawa, Kunimoto Hotta, Seiji Shibahara, Shinichi Kondo, Satoshi Nimura
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Publication number: 20120245113Abstract: The use or methods of use of extracts comprising one or more special clerodane compounds against inflammatory (including allergic) diseases or conditions, as well as novel compounds of this type, said clerodane derivatives for use against inflammatory (including allergic) diseases or conditions, pharmaceutical formulations comprising them especially for use against inflammatory disease or conditions, and related embodiments; said extract and/or compound(s) for use in the treatment or in the preparation of a medicament (including a nutraceutical) for the prophylactic and/or therapeutic treatment of said disease or condition, as well as their preparation; pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s) which are useful in said prophylactic and/or therapeutic treatment, and related embodiments.Type: ApplicationFiled: February 22, 2012Publication date: September 27, 2012Applicant: BIOTROPICS MALAYSIA BHDInventors: Matthias GEHLING, Torsten GROTHE, Ernst ROEMER, Peter REINEMER, Kathrin REINHARDT, Annie GEORGE, Nur Hanisah MOHTAR, Noorsyarida Mohd Sapiai
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Publication number: 20100267822Abstract: The invention relates to aurones and extracts comprising them useful in the prophylactic and/or therapeutic treatment of an animal (including a human) with an estrogen receptor (ER) related disease or condition of the animal or human body, as well as methods, uses and other inventions related thereto.Type: ApplicationFiled: March 29, 2010Publication date: October 21, 2010Inventors: Annie George D/O V.K. George, Bärbel Köpcke, Ernst Roemer, Jens Bitzer, Joachim Hans, Joerg Gruenwald, Matthias Gehling, Philipp Wabnitz, Tengku Shahrir bin Tengku Adnan, Torsten Grothe
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Publication number: 20100267823Abstract: The invention relates to aurones and extracts comprising them useful in the prophylactic and/or therapeutic treatment of an animal (including a human) with a phosphodiesterase (PDE) dependent disease or condition of the central nervous system, as well as methods, uses and other inventions related thereto.Type: ApplicationFiled: March 29, 2010Publication date: October 21, 2010Inventors: Annie George D/O V.K. George, Bärbel Köpcke, Ernst Roemer, Jens Bitzer, Joerg Gruenwald, Matthias Gehling, Philipp Wabnitz, Tengku Shahrir bin Tengku Adnan, Torsten Grothe
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Publication number: 20100144658Abstract: Seven novel antibiotic substances could be produced by cultivation of a microbial strain which has been isolated from a soil sample and which is designated as Microbispora sp. A 34030 (deposited under an access number FERM BP-10505 in terms of Budapest Treaty). These seven antibiotic substances are named as bispolide A1, bispolide A2, bispolide A3, bispolide B1, bispolide B2a, bispolide B2b and bispolide B3, respectively. These bispolides are each novel compounds which have a chemical structure as collectively represented by the general formula (III) shown below. These bispolides have each a high antibacterial activity against a variety of bacteria, particularly Gram-positive bacteria and their antibiotic-resistant strains, and hence these bispolides each are effective and useful for therapeutically treating bacterial infections of Gram-positive bacteria in human and animals.Type: ApplicationFiled: May 15, 2007Publication date: June 10, 2010Applicant: MITSUI CHEMICALS, INC.Inventors: Keiichi Numata, Noriyuki Okujo, Siew Eim Khor, Lee Li Tan, Annie George, Szu Ting Ng, Chin Jye Tan, Hironobu Iinuma, Yasuo Fukagawa, Kunimoto Hotta, Seiji Shibahara, Shinichi Kondo, Satoshi Nimura