Patents by Inventor Annie Sittler

Annie Sittler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Treating Polyglutamine Expansion Neurodegenerative Diseases
    Publication number: 20090208455
    Abstract: The present invention relates to use of an inducer of Promyelocytic Leukemia protein (PML) expression, and especially PML IV for the manufacture of a medicament intended for the treatment of polyglutamine expansion neurodegenerative diseases. More specifically, the present invention relates to the use of an interferon polypeptide for the manufacture of a medicament intended for the treatment of polyglutamine expansion neurodegenerative diseases.
    Type: Application
    Filed: June 22, 2007
    Publication date: August 20, 2009
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medical)
    Inventors: Alexandre Janer, Annie Sittler
  • Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation
    Publication number: 20040235813
    Abstract: The present invention relates to the use of a compound or a plurality of compounds that inhibit function of Hsp90; or activate expression of both Hsp40 and Hsp70 for the preparation of a pharmaceutical composition for the prevention or treatment of a disease associated with protein aggregation and amyloid formation. Preferably, said compound is geldanamycin. The present invention relates further to methods of producing compounds within proved potency and/or decreased side-effects that may be successfully employed as medicaments for the treatment of said diseases.
    Type: Application
    Filed: May 10, 2004
    Publication date: November 25, 2004
    Inventors: Erich Wanker, Annie Sittler, Ulrich Hartl