Patents by Inventor Annie Yang

Annie Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190365869
    Abstract: Shielding enzymes are made by modifying the enzyme surface with silica precursors and then depositing silica to a desired thickness while retaining biological activity of the enzyme.
    Type: Application
    Filed: June 1, 2019
    Publication date: December 5, 2019
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jacques Lux, Robert F. Mattrey, Annie Yang
  • Publication number: 20080200664
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotypes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Application
    Filed: August 25, 2006
    Publication date: August 21, 2008
    Inventors: Annie Yang, Frank McKeon
  • Publication number: 20080066116
    Abstract: An active digital TV antenna, the antenna mainly has a planar antenna and a variable capacitor connected to the planar antenna; the variable capacitor is used to adjust a capacitance value and an inductance value of the planar antenna to change the range of frequency band of a signal received by the planar antenna. Therefore, the entire volume of the antenna can be reduced to be suitable for applying in an active electronic machine such as a notebook or a mobile phone.
    Type: Application
    Filed: September 11, 2006
    Publication date: March 13, 2008
    Inventors: Chi-Ming Chiang, Annie Yang, Chih-Cheng Chien
  • Patent number: 7294459
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: November 13, 2007
    Assignee: President and Fellows of Harvard College
    Inventors: Annie Yang, Frank McKeon
  • Patent number: 7183049
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: February 27, 2007
    Assignee: President and Fellows of Harvard College
    Inventors: Annie Yang, Frank McKeon
  • Patent number: 7030227
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: April 18, 2006
    Assignee: President & Fellows of Harvard College
    Inventors: Frank McKeon, Annie Yang
  • Publication number: 20060019310
    Abstract: Disclosed herein are methods for diagnosing cancer in a biological sample comprising measuring the level of a p63 gene product in the sample.
    Type: Application
    Filed: April 19, 2005
    Publication date: January 26, 2006
    Inventors: Frank McKeon, Annie Yang, Massimo Loda, Sabina Signoretti, Christopher Crum
  • Publication number: 20050277116
    Abstract: The present invention relates to a two-hybrid system for studying protein-protein interactions in mammalian host cells. The invention provides methods, reagents and kits for carrying out the two-hybrid screen. Accordingly the invention provides a bait construct that is capable of targeting a bait protein to a specific subcellular locale within the host cell. The invention also provides a prey construct that contains a detection sequence fused to a prey protein. The bait and prey constructs are introduced into a host cell under conditions that promote expression of the bait and prey constructs. A positive bait/prey interaction can be detected by comparing the subcellular localization of the prey construct in relation to the bait construct. The invention also provides methods for screening for compounds capable of disrupting protein-protein interaction and methods for detecting interactions between proteins and small molecule compounds.
    Type: Application
    Filed: April 22, 2002
    Publication date: December 15, 2005
    Inventors: Frank McKeon, Annie Yang
  • Patent number: 6946256
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Grant
    Filed: March 29, 2000
    Date of Patent: September 20, 2005
    Assignees: President & Fellows of Harvard College, The Brigham and Women's Hospital, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: Frank McKeon, Annie Yang, Massimo Loda, Sabina Signorretti, Christopher Crum
  • Publication number: 20040132120
    Abstract: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
    Type: Application
    Filed: November 18, 2003
    Publication date: July 8, 2004
    Inventors: Annie Yang, Frank McKeon
  • Patent number: 6218993
    Abstract: A gain structure of a stretchable antenna for mobile phones and especially of an antenna for minimized mobile phones, wherein, a quarter-wave coil antenna is built in a hole of a connecting member on the top of a mobile phone, one end of the coil antenna is pressed against a metallic conductive block in the connecting member; a spring sheet has its top folded end fixed on the metallic conductive block, and has the other end thereof extended in a hole provided on the top of the mobile phone to abut on an internal electric circuit board under a pressing force. A quarter-wave rod antenna is connected to the connecting member to be freely movable in and out of it. When the rod antenna is stretched out, a metallic bottom end sleeve thereof is pressed into the metallic conductive block to make electric connection therewith, this can increase gain in signal receiving and emitting of the minimized mobile phone.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: April 17, 2001
    Assignee: Auden Technology Mfg. Co. Ltd.
    Inventors: Jack Chao, Annie Yang