Patents by Inventor Annika Björe

Annika Björe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxabispidine compounds for the treatment of cardiac arrhythmias
    Patent number: 7928225
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R41 to R46, X, Y and Z have meanings given in the description, which compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: April 19, 2011
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, David Cladingboel, Gareth Ensor, Adam Herring, Johan Kajanus, Robert Lundqvist, Christina Olsson, Carl-Gustav Sigfridsson, Gert Strandlund
  • Oxabispidine compounds useful in the treatment of cardiac arrhythmias
    Patent number: 7772229
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: August 10, 2010
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, Kurt-Jürgen Hoffmann, Fritiof Pontėn, Gert Strandlund, Peder Svensson, Michael Wilsterman
  • Oxabispidine compounds useful in the treatment of cardiac arrhythmias
    Patent number: 7351821
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: April 1, 2008
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, David Cladingboel, Kurt-Jürgen Hoffmann, John Pavey, Fritiof Pontén, Gert Strandlund, Peder Svensson, Colin Thomson, Michael Wilsterman
  • 3,7-Diazabicyclo [3.3.1] formulations as anti-arrhythmic compounds
    Patent number: 7217708
    Abstract: There is provided substantially crystalline forms of 4-({3-[7-(3,3-dimethyl-2-oxobutyl) -9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]propyl}amino)benzo-nitrile; tert-butyl 2 -{7-[3-(4-cyanoanilino)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate; tert-butyl 2-{7-[4-(4-cyanophenyl)butyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethylcarbamate; or tert-butyl 2-{7-[2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of cardiac arhythmias.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: May 15, 2007
    Assignee: Astrazeneca AB
    Inventors: Neil Barnwell, Annika Björe, Lal Cheema, David Cladingboel, Adam Herring, Karin Lövqvist
  • Oxabispidine compounds useful in the treatment of cardiac arrhyythmias
    Patent number: 6559143
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: May 6, 2003
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, Kurt-Jürgen Hoffmann, Fritiof Pontén, Gert Strandlund, Peder Svensson, Michael Wilsterman
  • Dried or frozen pharmaceutical preparation containing a class III antiarrhythmic compound
    Patent number: 6492382
    Abstract: The present invention relates to dried preparations containing a class III antiarrhythmic compound in the form of a crystalline or amorphous salt or any combination thereof, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. The present invention also relates to frozen preparations containing a class III antiarrhythmic compound in the form of a salt solution, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. Preferred preparations contain a salt of the compound 3,7-diazabicyclo[3.3.1]-nonane-3-carboxylic acid, 7-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-1,1-dimethylethyl ester (Compound A). Further aspects of the present invention include salts of Compound A per se, processes for preparing the preparations, as well as use of the preparations for prophylaxis and/or treatment of cardiac arrhytmia.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: December 10, 2002
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Anna-Karin Granath
  • Bispidine antiarrhythmic compounds
    Patent number: 6291475
    Abstract: There is provided a compound of formula I, wherein R1, R2, R9, R10, R11, R12, X, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: September 18, 2001
    Assignee: AstraZeneca AB
    Inventors: Christer Alstermark, Annika Björe, Magnus Björsne, Marianne Frantsi, Torbjörn Halvarsson, Kurt-Jürgen Hoffmann, Eva-Lotte Lindstedt, Magnus Polla, Gert Strandlund