Patents by Inventor Anning Lin

Anning Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of TNF- alpha cytotoxicity
    Patent number: 10751324
    Abstract: Provided herein is technology relating to treating and/or ameliorating TNF? cytotoxicity and particularly, but not exclusively, to compositions, methods, and kits for specifically modulating BCL-2-associated death promoter (BAD) activity, for example, by modulating the activity of Src and/or p190GAP.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: August 25, 2020
    Assignee: The University of Chicago
    Inventor: Anning Lin
  • TREATMENT OF TNF- alpha CYTOTOXICITY
    Publication number: 20190192484
    Abstract: Provided herein is technology relating to treating and/or ameliorating TNF? cytotoxicity and particularly, but not exclusively, to compositions, methods, and kits for specifically modulating BCL-2-associated death promoter (BAD) activity, for example, by modulating the activity of Src and/or p190GAP.
    Type: Application
    Filed: September 1, 2017
    Publication date: June 27, 2019
    Inventor: Anning Lin
  • Oncoprotein protein kinase antibody kit
    Patent number: 7468426
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: December 23, 2008
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • ONCOPROTEIN PROTEIN KINASE ANTIBODY KIT
    Publication number: 20080299584
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: September 15, 2006
    Publication date: December 4, 2008
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Publication number: 20070077581
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and Threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of deterction of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: September 15, 2006
    Publication date: April 5, 2007
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin, Roger Davis, Benoit Derijard
  • Oncoprotein protein kinase
    Publication number: 20060121527
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: February 3, 2006
    Publication date: June 8, 2006
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Publication number: 20050170381
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and Threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of deterction of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: October 21, 2004
    Publication date: August 4, 2005
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6863888
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: March 8, 2005
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin, Roger Davis, Benoit Derijard
  • Oncoprotein protein kinase
    Publication number: 20050032123
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: August 25, 2003
    Publication date: February 10, 2005
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6846644
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: January 25, 2005
    Assignee: The Regents of the University of California
    Inventors: Roger Davis, Benoit Derijard, Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6706509
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: March 16, 2004
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Publication number: 20030190735
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: May 18, 2001
    Publication date: October 9, 2003
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6610505
    Abstract: An isolated polypeptide (JNK characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: August 26, 2003
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Publication number: 20030044788
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: May 18, 2001
    Publication date: March 6, 2003
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6514745
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: February 4, 2003
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin, Roger Davis, Benoit Derijard
  • Oncoprotein protein kinase
    Publication number: 20020192218
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: May 18, 2001
    Publication date: December 19, 2002
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Publication number: 20020160397
    Abstract: An isolated polypeptide (JNK characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Application
    Filed: January 16, 2002
    Publication date: October 31, 2002
    Applicant: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6342595
    Abstract: The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a peptide of SEQ ID NO:1 comprising (a) culturing a host cell containing a polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set forth in SEQ ID NO: 10 under conditions which allow expression of the polynucleotide; and (b) obtaining the peptide of SEQ ID NO:1.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: January 29, 2002
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein kinase
    Patent number: 6193965
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD or 55 kD as determined by reducing SDS-PAGE, having serine and theonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: February 27, 2001
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin
  • Oncoprotein protein kinase
    Patent number: 6001584
    Abstract: An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD or 55 kD as determined by reducing SDS-PAGE, having serine and theonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: December 14, 1999
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Masahiko Hibi, Anning Lin