Patents by Inventor Anno de Jong

Anno de Jong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5073369
    Abstract: The present invention relates to the use of microbiologically prepared compounds and their mixtures, which are called efomycins, as performance promoters in farm animals and processes for their preparation, and furthermore new efomycins and their mixtures as new chemical compounds. The invention also relates to microorganisms which can be used for the preparation of the efomycins and their mixtures.
    Type: Grant
    Filed: March 17, 1986
    Date of Patent: December 17, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Frobel, Erwin Bischoff, Hartwig Muller, Olga Salcher, Anno De Jong, Friedrich Berschauer, Martin Scheer
  • Patent number: 4927810
    Abstract: An animal growth promoter, efomycin G, is obtained by culturing Streptomycetes strain BS 1261. Efomycin G has the following properties:(a) The empirical formula: C.sub.53 H.sub.86 O.sub.18(b) The mass spectrum (fast atom bombardment) Molecular weight+Na.sup.+ : 1033(c) The .sup.1 H-nuclear magnetic resonance spectrum, stated in parts per million, shown in FIG. 1.(d) The .sup.13 C-nuclear magnetic resonance spectrum, stated in parts per million shown in FIG. 2, with chemical shifts of the CC-NMR signals as follows:______________________________________ 170.0 77.9 65.9 32.9 7.0 145.4 73.4 48.5 19.4 144.7 71.2 43.6 19.1 131.9 70.6 41.9 16.8 121.1 70.1 41.1 16.7 99.6 69.9 38.8 15.1 99.5 66.9 38.5 13.4 93.6 66.5 36.2 9.0 93.3 66.4 33.0 8.9 ______________________________________ (ppm values are relative to tetramethylsilane at 0 ppm)(e) A UV absorption maximum at 251-254 nm in methanolic solution(f) The structure according to FIG. 3.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: May 22, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Frobel, Hartwig Muller, Erwin Bischoff, Olga Salcher, Anno de Jong, Friedrich Berschauer, Martin Scheer
  • Patent number: 4880840
    Type: Grant
    Filed: June 30, 1987
    Date of Patent: November 14, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans Lindel, Axel Ingendoh, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4863939
    Abstract: The growth of livestock is promoted by the new compounds of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl, halogen, halogenoalkyl, hydroxyl, cyano, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, halogenoalkoxy, halogenoalkylthio or NHSO.sub.2 -alkyl,R.sup.2 represents hydrogen, hydroxyl, alkoxy or the --NR.sup.11 R.sup.12 radical,R.sup.3 represents the radicals mentioned in the case of R.sup.1R.sup.4 represents hydroxyl, acyloxy or alkoxy,R.sup.5 represents hydrogen or alkyl,R.sup.6 represents hydrogen or alkyl,R.sup.7 represents hydrogen or alkyl,R.sup.8 represents hydrogen or alkyl,X represents C.sub.1 -C.sub.10 -alkylene or a direct bond,Y represents oxygen or a direct bond,R.sup.9 represents hydrogen, C.sub.1 -C.sub.10 -alkyl which is optionally substituted by hydroxyl, alkoxy, acyloxy or the --NR.sup.13 R.sup.14 radical, or represents the COR.sup.15 radical or the O--Z--R.sup.16 radical,Z represents C.sub.1 -C.sub.10 -alkylene, C.sub.1 -C.sub.
    Type: Grant
    Filed: July 30, 1987
    Date of Patent: September 5, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans Lindel, Werner Hallenbach, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4847291
    Abstract: Aryl ethanol-hydroxylamines of the formula ##STR1## in which Ar represents aryl or heteroaryl, each of which can optionally be substituted, andR represents alkyl, aryl, aralkyl, heteroaryl, heteroaralkyl or cycloalkyl, each of which can optionally be substituted,or physiologically tolerated salts thereof, exhibit animal growth-promoting properties. Intermediates therefor of the formula ##STR2## with the exception of phenyl and p-bromophenyl, are also new.
    Type: Grant
    Filed: July 11, 1986
    Date of Patent: July 11, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Axel Ingendoh, Hans Lindel, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4845262
    Abstract: The growth of livestock is promoted by the novel arylethanolamines of the formula ##STR1## in which R.sup.1 represents cyano,R.sup.2 represents amino, alkylamino or acylamino,R.sup.3 represents hydrogen, halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, hydroxymethyl, nitro or methylsulphonylmethyl,R.sup.4 represents hydrogen, alkyl or acyl,R.sup.5 represents hydrogen or alkyl,R.sup.6 represents alkyl,n represents 1, 2 or 3,R.sup.7 represents the radicals --COR.sup.9, --O-alkylene-COR.sup.9, -alkylene-R.sup.10 or --O-alkylene-R.sup.10,R.sup.8 represents hydrogen, alkyl or halogen,R.sup.9 represents hydroxyl, alkoxy or the radical --NR.sup.11 R.sup.12,R.sup.10 represents hydroxyl, alkoxy or the radical NR.sup.11 R.sup.12,R.sup.11 represents hydrogen or alkyl, andR.sup.12 represents hydrogen or alkyl,and the physiologically acceptable salts thereof.
    Type: Grant
    Filed: August 25, 1987
    Date of Patent: July 4, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans Lindel, Werner Hallenbach, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4806667
    Abstract: A method for promoting production of useful livestock comprising administering to such livestock an amount effective therefor of a monosilylated aminopheylethylamine derivative of the formula ##STR1## in which X and Y are identical or different and represent hydrogen or CN,R.sup.2 represents hydrogen or methyl,R.sup.3 represents t-butyl, isopropyl, monofluoro-t-butyl or 1-cyclohexyl-ethyl, andR.sup.4, R.sup.5 and R.sup.6 denote a straight-chain or branched alkyl rdical,or a physiologically tolerated salt thereof.Those compounds wherein R.sup.
    Type: Grant
    Filed: December 4, 1986
    Date of Patent: February 21, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Boshagen, Jurgen Stoltefuss, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4770876
    Abstract: Promoting the growth of animals with a novel compound, named annomycin, by cultivation of Streptomyces strain BS 572, DSM 3817.
    Type: Grant
    Filed: August 25, 1987
    Date of Patent: September 13, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Hartwig Muller, Olga Salcher, Friedrich Berschauer, Martin Scheer, Anno de Jong, Klaus Frobel
  • Patent number: 4760063
    Abstract: Novel thienooxazines of the formula ##STR1## in which R.sup.1 and R.sup.2, together with the adjacent C atoms, represent an optionally substituted thiophene ring,R.sup.3 represents hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl or aryl, andR.sup.4 represents optionally substituted alkyl, cycloalkyl, alkenyl or aryl, orR.sup.3 and R.sup.4, together with the adjacent nitrogen atom, form a saturated heterocyclic structure which may optionally contain further hetero atoms,promote the yield of animals, e.g. rate of growth, ratio of meat to fat, etc. They are made from new intermediates of the formulas ##STR2## in which R.sup.5 and R.sup.6 may be hydrogen or various organic radicals, or together form a ring.
    Type: Grant
    Filed: November 12, 1986
    Date of Patent: July 26, 1988
    Assignee: Bayer Aktiengsellschaft
    Inventors: Werner Hallenbach, Hans Lindel, Friedrich Berschauer, Martin Scheer, Anno de Jong
  • Patent number: 4680287
    Abstract: Growth of animals is promoted by inclusion in their feed of compounds of the formula ##STR1## in which Z is a glycosyl radical bonded via the anomeric carbon atom,R.sub.1 is hydrogen or an optionally substituted hydrocarbon radical having up to 30 Carbon atoms optionally interrupted by O, N or S, andR.sub.2 is hydrogen or an alkyl or aralkyl radical having up to 30 Carbon atoms optionally interrupted by O or substituted by groups containing oxygen or by halogen, with the proviso that COR.sub.1 is not an acyl group having 1-5 Carbon atoms when R.sub.2 is an alkyl group having 10-20 Carbon atoms.
    Type: Grant
    Filed: October 26, 1984
    Date of Patent: July 14, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Oswald Lockhoff, Peter Stadler, Martin Scheer, Friedrich Berschauer, Anno de Jong
  • Patent number: 4678797
    Abstract: Substituted isoxazolidines of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, cycloalkyl, aralkyl, aryl or heteroaryl or radicals of the formula --COR.sup.4,R.sup.4 represents optionally substituted alkyl, aryl, alkoxy, alkylthio, aroxy, arylthio, amino, alkylamino, dialkylamino, arylamino, arylalkylamino, diarylamino or cycloalkylamino, or optionally substituted heterocyclic radicals which are bonded via nitrogen,R.sup.2 represents hydrogen or the radicals mentioned for R.sup.1, it being possible for R.sup.1 and R.sup.2 to be identical or different, andR.sup.3 represents optionally substituted alkyl, cycloalkyl, alkenyl, alkinyl or aryl, or saturated heterocyclic radicals, which are optionally substituted,and acid salts thereof, are pesticidally active and increase animals' utilization of feed. Intermediates therefor are also new.
    Type: Grant
    Filed: May 10, 1985
    Date of Patent: July 7, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Axel Ingendoh, Friedrich Berschauer, Benedikt Becker, Wilhelm Stendel, Bernhard Homeyer, Martin Scheer, Anno de Jong, Gerd Hanssler, Paul Reinecke
  • Patent number: 4670423
    Abstract: Monosilylated aminophenylethylamine derivative of the formula ##STR1## in which X and Y each independently is hydrogen or halogen,R.sub.1 is the radical ##STR2## R.sub.2 is hydrogen or an aliphatic hydrocarbon radical having up to 10 C atoms,R.sub.3 is hydrogen, an aliphatic hydrocarbon radical which can optionally be substituted by halogen, a phenyl radical which can optionally be substituted by halogen, hydroxyl, alkyl, aryl, alkoxy, alkylthio, optionally substituted phenoxy, optionally substituted phenylthio, cyano or trifluoromethyl, or a heterocyclic radical, or, together with R.sub.2 is a nitrogen-containing saturated heterocyclic radical, andR.sub.4, R.sub.5 and R.sub.6 each independently is an alkyl radical,or physiologically tolerated salts thereof, promote the growth of animals.
    Type: Grant
    Filed: March 8, 1985
    Date of Patent: June 2, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Boshagen, Jurgen Stoltefuss, Friedrich Berschauer, Anno de Jong, Martin Scheer
  • Patent number: 4670260
    Abstract: A novel antibiotic for combating bacteria and promoting animal growth is obtained by cultivating Streptomyces strain BA 9.
    Type: Grant
    Filed: November 27, 1985
    Date of Patent: June 2, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Hartwig Muller, Olga Salcher, Friedrich Berschauer, Martin Scheer, Anno de Jong, Klaus Frobel