Abstract: A method of optimizing thermocline zone within a thermal storage system including a plurality of storage tanks fluidly coupled to one another m series, to effectively form a single tank having an equivalent height of the combined height of the plurality of storage tanks. The method including identifying a thermocline zone, computing an average temperature (Tave) of the thermocline zone, directing thermal storage fluid from a bottom of an initial storage tank through a heat source heat exchanger, and terminating fluid flow from the bottom of the initial storage tank and directing thermal storage fluid from a bottom of a first subsequent storage tank when a temperature of the thermal storage fluid exiting the bottom of the initial storage tank reaches Tave.

Abstract: A method of optimizing thermocline zone within a thermal storage system including a plurality of storage tanks fluidly coupled to one another m series, to effectively form a single tank having an equivalent height of the combined height of the plurality of storage tanks. The method including identifying a thermocline zone, computing an average temperature (Tave) of the thermocline zone, directing thermal storage fluid from a bottom of an initial storage tank through a heat source heat exchanger, and terminating fluid flow from the bottom of the initial storage tank and directing thermal storage fluid from a bottom of a first subsequent storage tank when a temperature of the thermal storage fluid exiting the bottom of the initial storage tank reaches Tave.

Abstract: This invention relates to pharmaceutical formulations comprising 1-(2-thien-2?-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2?-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof. The formulations of this invention are for treating diseases associated with advanced glycation end products.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: This invention relates to pharmaceutical formulations comprising 1-(2-thien-2?-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2?-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof.

Abstract: Wireless configuration tools for communicating with and configuring wireless device systems. An illustrative tool makes use of a software defined radio (SDR) to communicate in multiple formats, modes, or frequencies, with multiple wireless device systems that may otherwise be incompatible. In some embodiments, the tool determines what type and how many wireless systems are to be configured prior to configuration of any of the systems. The tool may then adjust how each system is configured to reduce intra-system as well as inter-system interference. Methods for performing such functions are also included.

Abstract: A wireless communications system comprising a number of node devices and a base station, and having a routing calculator, wherein the system is operating with a first routing map, the routing calculator gathers data relating to communications between node devices and determines whether route improvement is indicated and, if so, the routing calculator generates an improved routing solution, and instructions are relayed via the first routing map to the node devices for implementing a new routing map generated from the optimized routing solution. Also, a method of operating a wireless communication system, including a base station and a number of node devices the method comprising determining whether system improvement is indicated, if so, generating an improved system configuration, distributing data related to the improved system configuration to the node devices, and replacing the current communication configuration with the improved system configuration.

Abstract: Wireless communications methods and systems. Metrics for measuring performance of a wireless system are generated and compared to metrics generated with an idealized simulation of the system. If the actual system performance falls below a predetermined level, the system may be reconfigured to improve performance using a centralized or decentralized method for such configuration.

Abstract: A node in a wireless sensor network has a receiver that is at least partially implemented in high temperature superconductor circuitry. In one embodiment, band pass filters of the receiver are implemented in high temperature superconducting circuitry. In one embodiment, a cryo-cooler is coupled to a passage for providing coolant to the receiver such that the receiver is cooled at or below the superconducting temperature of its circuit elements.

Abstract: A locator system, including a transmitter device such as a PAS device to be carried by a first individual such as a first responder in a fire fighting event. The transmitter transmits an acoustic sound and a RF pulse. A RF receiver is carried by a second individual, such as someone dispatched to rescue the first individual. The receiver receives the acoustic sound using a pair of acoustic receivers and RF pulse and calculates the distance to and bearing of the transmitter device. Both transmitter and receiver may include temperature data for calculating the ambient speed of sound. A display informs the second individual of the distance and bearing. The acoustic sound receivers are spaced from each other to permit triangulation calculations to determine the distance and bearing. The transmitter is activated by the first individual by choice and when the first individual is motionless for a predetermined time.

Abstract: Monitoring systems and methods for monitoring one or more parameters within process equipment are disclosed. A monitoring system for wirelessly monitoring the process equipment can include a number of wireless sensors disposed within a fluid or gas process stream for monitoring various aspects of the fluid or gas medium such as temperature or pressure. Each of the wireless sensors can include a transmitter that can be used to wirelessly transmit sensor signals to a receiver in communication with a central monitoring unit. The wireless sensors can be placed directly within the fluid or gas medium, allowing accurate measurements to be taken within the process stream.

Abstract: The present invention pertains to the installation and positioning of the receivers of a wireless tracking system. In such a system, a wireless beaconing device transmits a signal that can be detected by a plurality of wireless receivers positioned at various known locations. Each wireless receiver records information derived from the signal from which it can make an estimate of the distance or relative position of the beaconing device. A controller correlates the information received from the multiple receivers and uses it to estimate the location of the individual. In such systems, the accuracy of the estimated position of the beaconing device depends on the accuracy to which the positions of the receivers are known. A technique is disclosed in which an installer carries a tracking device that can track the person's position and/or movements. The installer starts at a base location and resets the tracking device to cause the tracking device to record this position as the base position.

Abstract: In accordance with the principles of the invention, one or more individuals carry a wireless beaconing device that transmits a signal on a regular basis, such as every five seconds, that can be detected by a plurality of wireless receivers positioned at various locations in a household or other area. The receivers form nodes of a wireless network that further includes a control node. Each wireless receiver records the signal strength at which it receives the signal from the beaconing device and sends that information to the control node. The control node correlates this information and uses it to estimate the location of the individual. In this manner, the controller can track the location and movement of a person and provide that information to a caregiver or further process the data to analyze it for particular traits that might indicate that an individual is injured or otherwise in need of assistance.

Abstract: A system for self-calibration and self-tuning of sensors. The sensors may be calibrated statically and dynamically. The calibration may be automatic. Static calibration may be performed via a slope seeking loop. Dynamic calibration may be performed with both the slope seeking loop and a variation of the slope seeking set point.

Abstract: Wireless configuration tools for communicating with and configuring wireless device systems. An illustrative tool makes use of a software defined radio (SDR) to communicate in multiple formats, modes, or frequencies, with multiple wireless device systems that may otherwise be incompatible. In some embodiments, the tool determines what type and how many wireless systems are to be configured prior to configuration of any of the systems. The tool may then adjust how each system is configured to reduce intra-system as well as inter-system interference. Methods for performing such functions are also included.

Abstract: Wireless communications methods and systems. Metrics for measuring performance of a wireless system are generated and compared to metrics generated with an idealized simulation of the system. If the actual system performance falls below a predetermined level, the system may be reconfigured to improve performance using a centralized or decentralized method for such configuration.

Abstract: A wireless communications system comprising a number of node devices and a base station, and having a routing calculator, wherein the system is operating with a first routing map, the routing calculator gathers data relating to communications between node devices and determines whether route improvement is indicated and, if so, the routing calculator generates an improved routing solution, and instructions are related via the first routing map to the node devices for implementing a new routing map generated from the optimized routing solution. The improved routing solution may be optimized in light of one or more factors related to communications reliability and/or efficiency.