Abstract: A method of operating an engine includes operating the engine in first and second engine operating map regions by performing passive jet ignition combustion with a first stoichiometric fuel mixture and a first volume of residual gas. The engine is operated in a third engine operating map region by performing turbulent jet controlled compression ignition (TJCCI) with an ultra lean fuel mixture and a first volume of cooled exhaust gas recirculation, a fourth engine operating map region by performing passive jet ignition combustion with a third stoichiometric fuel mixture and a second volume of cooled exhaust gas recirculation, and a fifth engine operating map region, characterized by shutting off the engine. The engine is operated in a mode transition region between the second, third, and fourth engine operating map regions by performing passive jet ignition combustion with a second stoichiometric fuel mixture and a second volume of residual gas.

Abstract: An always on display method and an electronic device are provided. The method includes: An electronic device obtains text content. The electronic device performs word segmentation processing on the text content to obtain a plurality of word segments. The electronic device determines at least one layout format of the text content based on a quantity of words of the text content, a quantity of the plurality of word segments, and a preset mapping relationship. The at least one layout format includes a first layout format. The electronic device detects a screen lock operation. In response to the screen lock operation, the electronic device displays the text content on an always on display interface based on the first layout format.

Abstract: A motor system includes an engine having one or more cylinders, an electronic control unit, an exhaust treatment system in fluid connection with and downstream of the one or more cylinders. The exhaust treatment system includes an exhaust line, a combustion zone downstream, a combustion ignition source in the combustion zone, a catalyst downstream of an in thermal communication with the combustion zone. A method of heating a catalyst during an engine cold start and a method of initiating regular operating conditions of an engine having one or more cylinders are also described.

Abstract: Disclosed are a display apparatus and a method for controlling screen projections from multiple devices to a same screen. The display apparatus includes: a display and at least one processor configured to execute instructions to cause the display apparatus to: establish a connection with a first projection device; receive projection contents; control the display to show a top-level application of a user interface displayed, in a case that the projection content is vertical media resource; determine whether the top-level application supports split screen display; when the top-level application supports split screen display, the top-level application is displayed in a first window and the projection contents are displayed in a second window; when the top-level application does not support split screen display, the top level application after proportional reduction is displayed in either of the two windows, and the projection content are displayed in the other window of the two windows.

Abstract: A psychological stress estimation method includes obtaining a physiological signal of a user corresponding to a current moment, determining a first stress indicator of the user based on the current moment and a cyclic stress model of the user, determining a second stress indicator of the user based on the physiological signal of the user corresponding to the current moment and an instantaneous stress model of the user, where the physiological signal is an input of the instantaneous stress model, and determining the current stress indicator of the user based on the first stress indicator and the second stress indicator.

Abstract: Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the sample, and acquiring a structure image from a second OMAG scan of the sample. Data based on pixel intensity values from the flow image and pixel intensity values from the structure image are then plotted onto a graph and from the graph, may be differentiated into a first data group representing static structure signals and a second data group representing flow signals. The method then includes suppressing pixels in the flow image corresponding to the first data group. The flow signal may also be multiplied by a weighting factor to suppress artifacts in the image.

Abstract: A prechamber device includes an enclosure body and a cap forming an enclosed volume. The enclosure body has an orifice at one end. A precombustion chamber is defined within the enclosed volume and is in fluid communication with the orifice. A valve plug is movable along an axial axis of the enclosure body to adjust a valve opening at the orifice to a range of positions from a fully open position to a closed position. An actuator is coupled to the cap and the valve plug and is controllable to displace the valve plug along the axial axis of the enclosure body. The prechamber device is operable to generate turbulent jets that are directed into a main combustion chamber of an engine cylinder through the valve opening. During an engine cycle, the valve opening is controlled between the range of positions based on detected engine speed and engine load.

Abstract: A pre-prodrug, comprising a drug, e.g., doxorubicin, which has off-target toxicity (e.g., cardiotoxicity) with respect to its antineoplastic activity, and an amine functionality of the drug incorporated into a disubstituted maleimide (DMI). The pre-prodrug may be linked to a targeting or de-targeting agent or a polar modulator, e.g., charged ligand, amino acid, peptide, etc., to increase therapeutic index. The pre-prodrug is hydrolyzed to the prodrug, having a disubstituted maleamic acid (DMA). A polar modulator such as glutamic acid prevents cellular uptake of the prodrug, but not the doxorubicin drug released from the prodrug after dissociation. The prodrug is pH sensitive, and below pH 7.0, tends to cleave to form free drug and cyclized maleic anhydride. Tumor environments tend to be more acidic, e.g., pH 6.8, than cardiac tissue, e.g., pH 7.4, and therefore the heart is spared while the drug is selectively released within a tumor.

Abstract: An Image based handheld imager system is disclosed utilizing consumer-grade 2D camera arrays, while also addressing the problems of image quality, sensitivity, and imaging depth.

Abstract: A psychological pressure evaluation method includes obtaining a physiological parameter measurement value of a user, determining a psychological pressure evaluation model of the user based on a physiological parameter reference value of the user and a common psychological pressure evaluation model, where the common psychological pressure evaluation model reflects a change relationship between a psychological pressure value change amount and a physiological parameter value change amount, and determining a psychological pressure evaluation result of the user based on the physiological parameter measurement value of the user and the psychological pressure evaluation model of the user.

Abstract: The present invention is directed to an achromatic endoscope which employs a diffractive microlens. Along with a broadband rotary joint and a custom 800 nm SD-OCT system, ultrahigh-resolution 3D volumetric imaging over a large area becomes possible. The diffractive microlens can be used directly with a GRIN lens, making the endoscope design simpler and cost effective. Preliminary ex vivo 3D intraluminal imaging was performed with the endoscope in conjunction with a home-built broadband rotary joint and a spectral-domain OCT system, demonstrating the performance of the diffractive endoscope. Considering the miniature OCT imaging probe is the required component for using the OCT technology in internal organs, the proposed approach will have a broad impact on endoscopic OCT imaging by improving OCT resolution in any applications that involve a miniature OCT probe, as intravascular OCT imaging, gastrointestinal (GI) tract imaging, airway imaging etc.

Abstract: Systems and methods of producing medical images of a subject are disclosed herein. In one embodiment, structural data and vascular data are acquired from a region of interest in the subject. A filter is generated using structural image data acquired from a second layer and blood flow image data received from a first layer in the region of interest. The filter is applied to vascular image data acquired from a second, deeper layer in the region of interest to form an image of the second layer having reduced tailing artifacts relative to the unfiltered vascular image data.

Abstract: An Image based handheld imager system is disclosed utilizing consumer-grade 2D camera arrays, while also addressing the problems of image quality, sensitivity, and imaging depth.

Abstract: A psychological stress estimation method includes obtaining a physiological signal of a user corresponding to a current moment, determining a first stress indicator of the user based on the current moment and a cyclic stress model of the user, determining a second stress indicator of the user based on the physiological signal of the user corresponding to the current moment and an instantaneous stress model of the user, where the physiological signal is an input of the instantaneous stress model, and determining the current stress indicator of the user based on the first stress indicator and the second stress indicator.

Abstract: The present disclosure relates to blood pressure calibration period determining methods and devices. One example method includes obtaining, by a blood pressure measurement device, first physiological status information and second physiological status information of a tested person, where the first physiological status information is related information that causes a change in blood pressure of the tested person within a first time period after the blood pressure is calibrated, and where the second physiological status information is related information that causes a change in the blood pressure of the tested person within a second time period before the blood pressure is calibrated, and determining, by the blood pressure measurement device, a blood pressure calibration period based on a degree of change of the first physiological status information relative to the second physiological status information.

Abstract: Systems and methods of producing medical images of a subject are disclosed herein. In one embodiment, structural data and vascular data are acquired from a region of interest in the subject. A filter is generated using structural image data acquired from a second layer and blood flow image data received from a first layer in the region of interest. The filter is applied to vascular image data acquired from a second, deeper layer in the region of interest to form an image of the second layer having reduced tailing artifacts relative to the unfiltered vascular image data.

Abstract: Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the sample, and acquiring a structure image from a second OMAG scan of the sample. Data based on pixel intensity values from the flow image and pixel intensity values from the structure image are then plotted onto a graph and from the graph, may be differentiated into a first data group representing static structure signals and a second data group representing flow signals. The method then includes suppressing pixels in the flow image corresponding to the first data group. The flow signal may also be multiplied by a weighting factor to suppress artifacts in the image.

Abstract: The present invention is directed to an achromatic endoscope which employs a diffractive microlens. Along with a broadband rotary joint and a custom 800 nm SD-OCT system, ultrahigh-resolution 3D volumetric imaging over a large area becomes possible. The diffractive microlens can be used directly with a GRIN lens, making the endoscope design simpler and cost effective. Preliminary ex vivo 3D intraluminal imaging was performed with the endoscope in conjunction with a home-built broadband rotary joint and a spectral-domain OCT system, demonstrating the performance of the diffractive endoscope. Considering the miniature OCT imaging probe is the required component for using the OCT technology in internal organs, the proposed approach will have a broad impact on endoscopic OCT imaging by improving OCT resolution in any applications that involve a miniature OCT probe, as intravascular OCT imaging, gastrointestinal (GI) tract imaging, airway imaging etc.

Abstract: The invention relates to a stable recombinant host cell comprising a CYP24 nucleic acid. The host cell is preferably a mammalian cell or an insect cell. The cell is useful for identifying modulators of CYP24 that can be used in the treatment of CYP24 expression-related medical conditions.

Abstract: The invention relates to a stable recombinant host cell comprising a CYP24 nucleic acid. The host cell is preferably a mammalian cell or an insect cell. The cell is useful for identifying modulators of CYP24 that can be used in the treatment of CYP24 expression-related medical conditions.