Abstract: An example method of alerting and remediation in a multi-cloud computing system having a public cloud in communication with a data center includes: receiving, at remediation and troubleshooting software executing in the public cloud, event and log information generated by endpoint software executing in the data center during operation thereof; generating, at the remediation and troubleshooting software, an incident in response to the event and log information; sending, by a remediation and troubleshooting service (RTS) of the remediation and troubleshooting software in response to the incident, a remediation task to a coordinator agent over a message fabric, the coordinator agent executing in an agent platform appliance of the data center; and executing, by the coordinator agent, remediation of the endpoint software according to the remediation task.