Abstract: The systems and methods perform Bayesian anatomically-driven, artificial-intelligence based intracardiac echocardiography object detection and prediction. The system proposes hypotheses for what features and objects are in view based on prior knowledge informed by previously acquired or generated models. During a cardiac interventional procedure, the system uses a per-frame object identification artificial intelligence (AI); the gathered data is analyzed within a Bayesian framework to create updated posterior prediction(s) of what feature(s) may be predicted (with a computed confidence level) to be in view and their respective location(s). Inferences that pass an accept/reject threshold for object identification and meet minimum threshold settings for temporal stability and spatial location are used to display labels and boundaries. The system predicts what features and objects are in-frame, where out-of-frame objects/features may be located, and how to navigate to them.

Abstract: Systems and methods of 3D ultrasound imaging with one or more “thick-slice” 3D ultrasound imaging zones and one or more 2D ultrasound zones using a multi-zone, multi-frequency image reconstruction scheme with subzone blending. The first zone can be a thick-slice imaging zone and the second and third zones are 2D imaging zones. The first zone and the second zone can be thick-slice imaging zones and the third zone can be a 2D imaging zone. The first zone can be a 2D imaging zone, the second zone can be a thick-slice imaging zone and the third zone can be a 2D imaging zone. A method includes imaging a first zone using plane wave imaging, a second zone using tissue harmonic imaging, and a third zone using fundamental and subharmonic deep imaging. The depth of each zone can vary based on the ultrasonic array and the F # used for imaging the zone.

Abstract: An intracardiac echocardiography (“ICE”) catheter device including a flexible circuit sized for insertion into a vessel of a patient. The flexible circuit can have a transducer array positioned on the outer surface of the flexible circuit at a proximal region. A cable connection portion can be positioned at a distal region of the flexible circuit, where a plurality of traces can couple the transducer array to the cable connection portion. The arrangement of the plurality of traces, which couple the transducer array and the cable connection portion, can improve the signal processing time of the ICE catheter device which can result in better imaging.

Abstract: Systems and methods are disclosed for reducing a comet tail aberration in an image of an ablation catheter. In one example, the method includes receiving ICE images depicting the ablation catheter tip and an area proximate to the ablation catheter tip; automatically determining, by the computer system, a location of the tip of the ablation catheter in the received ICE images; automatically determining, by the computer system, the presence of a comet tail aberration in a region of interest (ROI) near the ablation catheter tip in the received ICE images; and in response to determining the aberration is present in the ROI, automatically changing, by the computer system, an imaging characteristic of the ICE imaging system to affect the appearance of the aberration in the ROI in subsequent images generated by the ICE imaging system using the changed imaging characteristic.

Abstract: Systems and methods of 3D ultrasound imaging with one or more “thick-slice” 3D ultrasound imaging zones and one or more 2D ultrasound zones using a multi-zone, multi-frequency image reconstruction scheme with subzone blending. The first zone can be a thick-slice imaging zone and the second and third zones are 2D imaging zones. The first zone and the second zone can be thick-slice imaging zones and the third zone can be a 2D imaging zone. The first zone can be a 2D imaging zone, the second zone can be a thick-slice imaging zone and the third zone can be a 2D imaging zone. A method includes imaging a first zone using plane wave imaging, a second zone using tissue harmonic imaging, and a third zone using fundamental and subharmonic deep imaging. The depth of each zone can vary based on the ultrasonic array and the F# used for imaging the zone.

Abstract: Systems and methods of ultrasound imaging of an object that includes multiple depth zones. Each of the zones can be imaged using a different frequency, or the same frequency as another zone. A method includes imaging a first zone using plane wave imaging, imaging a second zone using tissue harmonic imaging, and imaging a third zone using fundamental and subharmonic deep imaging. The depth of each zone can vary based on the ultrasonic array, and correspondingly, the F # used for imaging the zone. In an example, zones can be imaged at different F #'s, for example, at F #1 for the first zone, at F #2, F #3, or F #6 for one or more zones that extend deeper into the object than the first zone. The method can also include forming an image based on the received signals from the multiple zones, and blending the transitions between the zones.

Abstract: Systems and methods are described for implementing an “arc jump” technique in conjunction with bounded loads in consistent hashing. In general, bounded loads refers to limiting the ability of a single device within a distributed system to store data objects, such that when a request to store a new data object would otherwise be directed to that device, it is instead redirected to an alternative device. Redirecting all requests to a single alternative device can lead to cascading failures, as the alternative device must maintain its own load and that which has been redirected to it. Embodiments of the present disclosure address this by determining an alternative device on a per-object basis, such as by again hashing the object with an additional seed value. This distributes request from an overloaded device among all other devices of the distributed system, avoiding cascading failures.

Abstract: Systems and methods are described for load balancing requests in a distributed system using consistent hashing. Specifically, systems and methods are described for using “the power of k choices” when placing new servers on a consistent hash ring used to load balance requests. Rather than placing each new server at a fixed point determined by a hashing algorithm, a load balancer can identify multiple potential points on the hash ring for the new server. The load balancer can then compare these points to determine a preferred location, and place the server at the preferred location. Techniques described herein can substantially improve placement of servers, which in turn results in better load balancing.

Abstract: A device, system, and methods are described to perform machine-learning camera-based indoor mobile positioning. The indoor mobile positioning may utilize inexact computing, wherein a small decrease in accuracy is used to obtain significant computational efficiency. Hence, the positioning may be performed using a smaller memory overhead at a faster rate and with lower energy cost than previous implementations. The positioning may not involve any communication (or data transfer) with any other device or the cloud, providing privacy and security to the device. A hashing-based image matching algorithm may be used which is cheaper, both in energy and computation cost, over existing state-of-the-art matching techniques. This significant reduction allows end-to-end computation to be performed locally on the mobile device.

Abstract: A device, system, and methods are described to perform machine-learning camera-based indoor mobile positioning. The indoor mobile positioning may utilize inexact computing, wherein a small decrease in accuracy is used to obtain significant computational efficiency. Hence, the positioning may be performed using a smaller memory overhead at a faster rate and with lower energy cost than previous implementations. The positioning may not involve any communication (or data transfer) with any other device or the cloud, providing privacy and security to the device. A hashing-based image matching algorithm may be used which is cheaper, both in energy and computation cost, over existing state-of-the-art matching techniques. This significant reduction allows end-to-end computation to be performed locally on the mobile device.

Abstract: Described herein is a method and system for capturing, labeling, measuring and/or comparing images from current and/or previous ultrasound studies using a touch-screen user interface and a display where actions on the touch-screen input data on a captured ultrasound image on the display. Labels and measurements input on the touch-screen user interface are placed in the appropriate location on the captured ultrasound image and on an anatomically matching graphical representation on the touch-screen user interface either or both of which may be used to generate documentation and reports of an ultrasound study.

Abstract: A method for enabling contextual interaction on an electronic device is provided. The method includes detecting a context indicative of user activities associated with the electronic device and identifying one or more functions from a pre-defined set of functions based on the detected context. Further, the method also includes causing to display the one or more functions, where the one or more functions are capable of executing at least one of applications or services for accessing content relevant to the context, and dynamically performing an action relevant to the context in response to an interaction with a function.

Abstract: Methods and systems for storing and processing a plurality of fractions of imaging data thereby minimizing the amount of cache memory necessary while controlling data loss and the resulting image quality.

Abstract: A device, system, and methods are described to perform machine-learning camera-based indoor mobile positioning. The indoor mobile positioning may utilize inexact computing, wherein a small decrease in accuracy is used to obtain significant computational efficiency. Hence, the positioning may be performed using a smaller memory overhead at a faster rate and with lower energy cost than previous implementations. The positioning may not involve any communication (or data transfer) with any other device or the cloud, providing privacy and security to the device. A hashing-based image matching algorithm may be used which is cheaper, both in energy and computation cost, over existing state-of-the-art matching techniques. This significant reduction allows end-to-end computation to be performed locally on the mobile device.

Abstract: Described herein is a method and system for capturing, labeling, measuring and/or comparing images from current and/or previous ultrasound studies using a touch-screen user interface and a display where actions on the touch-screen input data on a captured ultrasound image on the display. Labels and measurements input on the touch-screen user interface are placed in the appropriate location on the captured ultrasound image and on an anatomically matching graphical representation on the touch-screen user interface either or both of which may be used to generate documentation and reports of an ultrasound study.

Abstract: Methods and systems for storing and processing a plurality of fractions of imaging data thereby minimizing the amount of cache memory necessary while controlling data loss and the resulting image quality.

Abstract: Techniques are disclosed for forming integrated passive devices, such as inductors and capacitors, using next-generation lithography (NGL) processes, such as electron-beam direct write (EBDW) and extreme ultraviolet lithography (EUVL). The techniques can be used to form various different integrated passive devices, such as inductors (e.g., spiral inductors) and capacitors (e.g., metal finger capacitors), having higher density, precision, and quality factor (Q) values than if such devices were formed using 193 nm photolithography. The high Q and dense passive devices formed can be used in radio frequency (RF) and analog circuits to boost the performance of such circuits. The increased precision may be realized based on an improvement in, for example, line edge roughness (LER), achievable resolution/critical dimensions, sharpness of corners, and/or density of the formed structures.

Abstract: Disclosed is a process for the upgrading and demetallizing of heavy oils and bitumens. A crude heavy oil and/or bitumen feed is supplied to a solvent extraction process 104 wherein DAO and asphaltenes are separated. The DAO is supplied to an FCC unit 106 having a low conversion activity catalyst for the removal of metals contained therein. The demetallized distillate fraction is supplied to a hydrotreater 110 for upgrading and collected as a synthetic crude product stream. The asphaltene fraction can be supplied to a gasifier 108 for the recovery of power, steam and hydrogen, which can be supplied to the hydrotreater 110 or otherwise within the process or exported. An optional coker unit 234 can be used to convert excess asphaltenes and/or decant oil to naphtha, distillate and gas oil, which can be supplied to the hydrotreater 220.

Abstract: The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl; R2 is hydrogen, benzyl or substituted benzyl, linear or branched (C1-C6) alkyl, substituted alkyl, aryl, substituted aryl, heterocycle and substituted heterocycle, useful for treatment of various disorders including cancer, multi-drug resistant cancers, viral infections etc. The invention also provides a process for the preparation of compounds of formula (I) and pharmaceutical compositions comprising the same.

Abstract: Disclosed is a process for the upgrading of heavy oils and bitumens, where the total feed to the process can include heavy oil or bitumen, water, and diluent. The process can include the steps of solvent deasphalting 110 the total feed 105 to recover an asphaltene fraction 116, a deasphalted oil fraction 118 essentially free of asphaltenes, a water fraction 112, and a solvent fraction 114. The process allows removal of salts from the heavy oils and bitumens either into the aqueous products or with the asphaltene product.