Patents by Inventor Anssi RANTASALO

Anssi RANTASALO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterologous production of psilocybin
    Patent number: 11952580
    Abstract: A recombinant host cell is disclosed for producing psilocybin and related compounds, such as metabolic intermediates of the psilocybin biosynthesis. Also provided is a method of producing psilocybin and its synthesis intermediates and related compounds, such as metabolic intermediates of the psilocybin biosynthesis, in the host cell, as well as a production system for producing them.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: April 9, 2024
    Assignee: TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
    Inventors: Dominik Mojzita, Heiko Rischer, Anssi Rantasalo, Kirsi-Marja Oksman-Caldentey, Joosu Kuivanen
  • Expression system for eukaryotic organisms
    Patent number: 11332750
    Abstract: The present invention provides an expression system for a eukaryotic host, which comprises 1) an expression cassette comprising a core promoter, the core promoter controlling the expression of a DNA sequence encoding a synthetic transcription factor (sTF), and 2) one or more expression cassettes each comprising a DNA sequence encoding a desired product operably linked to a synthetic promoter, the synthetic promoter comprising a core promoter, and sTF-specific binding sites upstream of the core promoter. The present invention also provides a method for identifying universal core promoters for eukaryotic hosts, expression systems using universal core promoters, hosts comprising the systems, and methods for producing protein products in eukaryotic hosts.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: May 17, 2022
    Assignee: Teknologian Tutkimuskeskus VTT OY
    Inventors: Dominik Mojzita, Anssi Rantasalo, Jussi Jäntti, Christopher Landowski, Joosu Kuivanen
  • HETEROLOGOUS PRODUCTION OF PSILOCYBIN
    Publication number: 20210010015
    Abstract: A recombinant host cell is disclosed for producing psilocybin and related compounds, such as metabolic intermediates of the psilocybin biosynthesis. Also provided is a method of producing psilocybin and its synthesis intermediates and related compounds, such as metabolic intermediates of the psilocybin biosynthesis, in the host cell, as well as a production system for producing them.
    Type: Application
    Filed: March 11, 2019
    Publication date: January 14, 2021
    Inventors: Dominik MOJZITA, Heiko RISCHER, Anssi RANTASALO, Kirsi-Marja OKSMAN-CALDENTEY, Joosu KUIVANEN
  • Expression system for eukaryotic organisms
    Publication number: 20180371468
    Abstract: The present invention provides an expression system for a eukaryotic host, which comprises 1) an expression cassette comprising a core promoter, said core promoter controlling the expression of a DNA sequence encoding a synthetic transcription factor (sTF), and 2) one or more expression cassettes each comprising a DNA sequence encoding a desired product operably linked to a synthetic promoter, said synthetic promoter comprising a core promoter, and sTF-specific binding sites upstream of the core promoter. The present invention also provides a method for identifying universal core promoters for eukaryotic hosts, expression systems using universal core promoters, hosts comprising said systems, and methods for producing protein products in eukaryotic hosts.
    Type: Application
    Filed: February 21, 2017
    Publication date: December 27, 2018
    Applicant: Teknologian tutkimuskeskus VTT Oy
    Inventors: Dominik MOJZITA, Anssi RANTASALO, Jussi JÄNTTI, Christopher LANDOWSKI, Joosu KUIVANEN