Patents by Inventor Anthony Amoroso

Anthony Amoroso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for down-regulation of CCR5 expression and methods of use thereof
    Patent number: 7863242
    Abstract: The present invention relates to the downregulation of surface receptor CCR5 expression through manipulation of the cell cycle in activated lymphocytes by administering a composition that arrests the G1 phase of the cell cycle, thereby reducing receptor sites for entry of HIV into T cells, and thus, the effects of HIV. Further, compositions are disclosed that include at least one G1 phase arresting agent and at least one antiviral agent, wherein the combination of agents synergistically enhances the activity of the antiviral agent.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: January 4, 2011
    Assignee: University of Maryland, Baltimore
    Inventors: Robert R. Redfield, Anthony Amoroso, Charles E. Davis, Alonso Heredia
  • Compositions for down-regulation of CCR5 expression and methods of use thereof
    Publication number: 20060154857
    Abstract: The present invention relates to the downregulation of surface receptor CCR5 expression through manipulation of the cell cycle in activated lymphocytes by administering a composition that arrests the G1 phase of the cell cycle, thereby reducing receptor sites for entry of HIV into T cells, and thus, the effects of HIV. Further, compositions are disclosed that include at least one G1 phase arresting agent and at least one antiviral agent, wherein the combination of agents synergistically enhances the activity of the antiviral agent.
    Type: Application
    Filed: November 16, 2005
    Publication date: July 13, 2006
    Applicant: University of Maryland Biotechnology Institute
    Inventors: Robert Redfield, Anthony Amoroso, Charles Davis, Alonso Heredia
  • Compositions for inducing increased levels of beta-chemokines and methods of use therefor
    Publication number: 20060099170
    Abstract: The present invention relates to compositions and methods for inducing increased levels and availability of ?-chemokines by administering to a subject at least one G1 phase arresting compound, wherein the increased levels and availability of ?-chemokines block chemokine/viral receptors thereby preventing or treating viral infections.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 11, 2006
    Inventors: Robert Redfield, Anthony Amoroso, Charles Davis, Alonso Heredia