Abstract: Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process.

Abstract: Disclosed herein is an article including a path that extends across at least a portion of a surface of the article, the path being defined by at least one channel that traverses at least a portion of the surface or a first plurality of spaced features disposed on or in at least a portion of the surface; the spaced features arranged in a plurality of groupings; the groupings of features comprising repeat units; the spaced features within a grouping being spaced apart at an average distance of about 1 nanometer to about 500 micrometers to define a path that traverses the plurality of spaced features; each feature having a surface that is substantially parallel to a surface on a neighboring feature; each feature being separated from its neighboring feature; the groupings of features being arranged with respect to one another so as to define a tortuous pathway.

Abstract: Disclosed herein a composition comprising a urethane of the FIG. 3; where hydroxyl or amine linkages on the urethane of the FIG. 3 are functionalized with molecules that contain fluorine atoms, phosphorus atoms, sulfur atoms, unsaturated carboxylic acids, derivatives of unsaturated carboxylic acids, or combinations thereof. Disclosed herein too is a composition comprising a urethane of the FIG. 3; where hydroxyl or amine linkages of the urethane of the FIG. 3 are functionalized with molecules that contain fluorine atoms, phosphorus atoms, sulfur atoms, unsaturated carboxylic acids, derivatives of unsaturated carboxylic acids, or combinations thereof; and a polymeric resin.

Abstract: Disclosed herein is an article that includes a first plurality of spaced features. The spaced features are arranged in a plurality of groupings; the groupings of features include repeat units; the spaced features within a grouping are spaced apart at an average distance of about 1 nanometer to about 500 micrometers; each feature having a surface that is substantially parallel to a surface on a neighboring feature; each feature being separated from its neighboring feature; the groupings of features being arranged with respect to one another so as to define a tortuous pathway. The plurality of spaced features provide the article with an engineered roughness index of about 5 to about 20.

Abstract: Generally, an intraocular implant having on the external surface a plurality of pattern surface elements disposed in spaced apart relation defining a tortuous pathway adapted to control a flow of fluid, or a flow of particles suspended in a fluid, or inhibits the growth or migration of cells. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits growth or migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: Disclosed herein is an article comprising a substrate; a polymer disposed upon the substrate; the polymer having a number average molecular weight of about 2,000 to about 5,000 grams per mole; where each polymer is separated from a neighboring polymer by an average distance of 2.5 Angstroms to 5,000 Angstroms. Disclosed herein is a method comprising disposing upon a substrate a polymer; the polymer having a number average molecular weight of 2,000 to about 5,000 grams per mole.

Abstract: Disclosed herein is an article that includes a first plurality of spaced features. The spaced features are arranged in a plurality of groupings; the groupings of features include repeat units; the spaced features within a grouping are spaced apart at an average distance of about 1 nanometer to about 500 micrometers; each feature having a surface that is substantially parallel to a surface on a neighboring feature; each feature being separated from its neighboring feature; the groupings of features being arranged with respect to one another so as to define a tortuous pathway. The plurality of spaced features provide the article with an engineered roughness index of about 5 to about 20.

Abstract: An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 ?m and 100 ?m in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article.

Abstract: Disclosed herein is a method comprising transporting a conduit and a template through a guide tube; the template being disposed on an outer surface of the conduit between the conduit and the guide tube; and transferring a texture from the template to the conduit as the conduit and the template are transported through the guide tube. Disclosed herein too is an apparatus comprising a guide tube; the guide tube being operative to facilitate a transfer of a pattern from a template to a conduit; a first feed spool and a first take-up spool for feeding the conduit through the guide tube and for taking up the conduit after it has travelled through the guide tube respectively; and a second feed spool and a second take-up spool for feeding the template through the guide tube and for taking up the template after it has travelled through the guide tube respectively.

Abstract: Disclosed herein is an article comprising a substrate; a polymer disposed upon the substrate; the polymer having a number average molecular weight of about 2,000 to about 5,000 grams per mole; where each polymer is separated from a neighboring polymer by an average distance of 2.5 Angstroms to 5,000 Angstroms. Disclosed herein is a method comprising disposing upon a substrate a polymer; the polymer having a number average molecular weight of 2,000 to about 5,000 grams per mole.

Abstract: Disclosed herein is an article that includes a first plurality of spaced features. The spaced features are arranged in a plurality of groupings; the groupings of features include repeat units; the spaced features within a grouping are spaced apart at an average distance of about 1 nanometer to about 500 micrometers; each feature having a surface that is substantially parallel to a surface on a neighboring feature; each feature being separated from its neighboring feature; the groupings of features being arranged with respect to one another so as to define a tortuous pathway. The plurality of spaced features provide the article with an engineered roughness index of about 5 to about 20.

Abstract: A method for forming reduced creep high molecular weight polyethylene articles, involves irradiating a high molecular weight polyethylene fiber or block, where the polyethylene is polycrystalline with a preferred crystal orientation. The fiber or block is irradiated in an environment including a molecule with a dual reactive functionality to provide cross-linking in the amorphous regions and/or on the surface and an inert gas at a temperature that is below an average alpha transition temperature of the polyethylene. The irradiation can be carried out on a polyethylene fiber by drawing a fiber through a solution containing a grafting agent that can include a molecule with a dual reactive functionality to primarily apply and cross-link the grafting material to the surface of the fiber. The resulting high molecular weight polyethylene article is highly cross linked and includes a plurality of substantially aligned crystals, the article providing an X-ray diffraction pattern evidencing only 2 sharp reflections.

Abstract: An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 ?m and 100 ?m in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article.

Abstract: An article has a curved surface. Disposed upon the curved surface is a plurality of patterns. Each pattern is defined by a plurality of spaced apart features attached to or projected into the curved surface. The plurality of features each have at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent features is about 1 nanometer and about 1 millimeter in at least a portion of the curved surface. The plurality of spaced apart features are represented by a periodic function.

Abstract: An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 ?m and 100 ?m in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article.

Abstract: A method of destroying target microorganisms comprises the step of contacting at least one target microorganism with at least one low molecular weight silanol end group containing molecule. The silanol containing molecule is selected from silanols (R1R2R3SiOH), siloxanediols HO(R1R2SiO)nH or siloxanols HO(R1R2SiO)nSiR1R2R3, where R1, R2 and R3 are selected from 1 to 4 carbon alkyl or fluoroalkyl moieties, or vinyl, or aryl groups and n is <6 . The silanol end group containing molecule can be triethylsilanol, diphenylmethylsilanol, t-butyldimethylsilanol, n-butyldimethylsilanol, n-propyldimethylsilanol, ethyldimethylsilanol, vinylphenylmethylsilanol, phenyldimethylsilanol, 3,3,3 trifluoro propyldimethylsilanol, benzyldimethylsilanol and phenethyldimethylsilanol, or mixtures thereof. A composition of matter includes a silanol end group containing molecule according to the invention blended with a polymer or dissolved in aqueous solution along with an ether-based cosolvent.

Abstract: Amino acid functionalized polymers useful for graft copolymerization prepared by reacting a mixture containing, for chain transfer, a thio-substituted amino acid and an ethylenically unsaturated monomer.

Abstract: A coated surface for resisting or enhancing bioadhesion includes at least one patterned polymer including coating layer having a plurality of features attached to or projected into a base surface. The features each have at least one microscale (<1 mm) dimension and have at least one neighboring feature having a substantially different geometry. The patterned coating layer preferably provides an average roughness factor (R) of from 4 to 50. The coating layer resists or enhances bioadhesion as compared to the base surface.

Abstract: A dynamic coating includes at least one polymeric layer for attachment to a surface. The polymeric layer includes at least one electrically conducting polymer including layer, wherein under influence of a dynamic signal applied to the polymeric layer, a contact angle of the polymeric layer dynamically and substantially increases or decreases upon oxidation or reduction of the polymer. The polymeric layer can also expand or contract upon oxidation or reduction. The coating can be used for a variety of applications including a non-toxic biofouling preventative system and for forming low voltage electrowetting pumps.

Abstract: Amino acid functionalized polymers useful for graft copolymerization prepared by reacting a mixture containing, for chain transfer, a thio-substituted amino acid and an ethylenically unsaturated monomer.