Patents by Inventor Anthony Cheung

Anthony Cheung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTESTINAL EXPRESSION OF PROGRAMMED DEATH LIGAND 1
    Publication number: 20230416337
    Abstract: Provided herein are methods and compositions for the amelioration of inflammatory disorders comprising the intestinal expression of programmed death ligand 1.
    Type: Application
    Filed: March 14, 2023
    Publication date: December 28, 2023
    Inventors: Shauna Marie DAUPHINEE, Connor Daniel Alexander MCCARTHY, Jeremy DUPAUL-CHICOINE, Eric HSU, Ghania CHIKH, Anthony CHEUNG
  • DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO
    Publication number: 20230414769
    Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: March 23, 2023
    Publication date: December 28, 2023
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • LOCALIZED EXPRESSION OF THERAPEUTIC NUCLEIC ACIDS IN LUNG EPITHELIAL CELLS
    Publication number: 20230210995
    Abstract: Provided herein are methods and compositions for the treatment of lung disorders comprising the expression of therapeutic nucleic acid(s) in human airway epithelial cells, including the treatment of cystic fibrosis and disorders caused by expression of a mutated CFTR gene comprising the expression of functional CFTR in human airway epithelial cells.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 6, 2023
    Inventors: Anthony CHEUNG, Jose Lora
  • Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo
    Patent number: 11623011
    Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: April 11, 2023
    Assignee: ENGENE, INC.
    Inventors: Jun Gao, Eric Hsu, Anthony Cheung
  • Intestinal expression of programmed death ligand 1
    Patent number: 11603398
    Abstract: Provided herein are methods and compositions for the amelioration of inflammatory disorders comprising the intestinal expression of programmed death ligand 1.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: March 14, 2023
    Inventors: Shauna Marie Dauphinee, Connor Daniel Alexander McCarthy, Jeremy Dupaul-Chicoine, Eric Hsu, Ghania Chikh, Anthony Cheung
  • REVERSIBLE COATING OF CHITOSAN-NUCLEIC ACID NANOPARTICLES AND METHODS OF THEIR USE
    Publication number: 20220395584
    Abstract: Chitosan-nucleic acid polyplex compositions containing a reversibly bound polymer coat comprising linear block copolymers with a polyanionic anchor region and at least one polyethylene glycol tail region are described herein. In some cases, the compositions exhibit improved stability and/or mucosal diffusion as compared to uncoated particles. In some cases, the reversibly bound polymer coat does not interfere with, or enhances, transfection of target cells or tissues as compared to uncoated particles.
    Type: Application
    Filed: March 13, 2020
    Publication date: December 15, 2022
    Inventors: Rajesh Krishnan Gopalakrishna PANICKER, Daniel VEILLEUX, Pei Lian MA, Natalie Chin Mun TAM, Carlos FLEET, Anthony CHEUNG
  • CHITOSAN POLYPLEX-BASED LOCALIZED EXPRESSION OF IL-12 ALONE OR IN COMBINATION WITH TYPE-I IFN INDUCERS FOR TREATMENT OF MUCOSAL CANCERS
    Publication number: 20220370637
    Abstract: The present disclosure relates to methods and compositions comprising derivatized-chitosan polyplexes reversibly coated with a polyanion-containing block co-polymer for the localized expression of IL-12 in mucosal tissues, preferably in combination with an IFN-1 activator/inducer, for use in cancer immunotherapy.
    Type: Application
    Filed: March 13, 2020
    Publication date: November 24, 2022
    Inventors: Rajesh Krishnan Gopalakrishna PANICKER, Daniel VEILLEUX, Pei Lian MA, Natalie Chin Mun TAM, Carlos FLEET, Anthony CHEUNG, Shauna DAUPHINEE, Ximin CHEN, Jose LORA
  • DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO
    Publication number: 20220133907
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: November 8, 2021
    Publication date: May 5, 2022
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo
    Patent number: 11167045
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: November 9, 2021
    Inventors: Jun Gao, Eric Hsu, Anthony Cheung
  • High concentration chitosan-nucleic acid polyplex compositions
    Patent number: 10647785
    Abstract: The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provides are methods for altering the diameter of chitosan-nucleic acid polyplexes.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: May 12, 2020
    Assignee: ENGENE, INC.
    Inventors: Eric Hsu, Carlos Fleet, Anthony Cheung, Jun Gao
  • DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO
    Publication number: 20200061208
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 27, 2020
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO
    Publication number: 20200054759
    Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 20, 2020
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo
    Patent number: 10456481
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: October 29, 2019
    Inventors: Jun Gao, Eric Hsu, Anthony Cheung
  • Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo
    Patent number: 10456478
    Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: October 29, 2019
    Inventors: Jun Gao, Eric Hsu, Anthony Cheung
  • INTESTINAL EXPRESSION OF PROGRAMMED DEATH LIGAND 1
    Publication number: 20190263887
    Abstract: Provided herein are methods and compositions for the amelioration of inflammatory disorders comprising the intestinal expression of programmed death ligand 1.
    Type: Application
    Filed: November 9, 2017
    Publication date: August 29, 2019
    Inventors: Shauna Marie DAUPHINEE, Connor Daniel Alexander MCCARTHY, Jeremy DUPAUL-CHICOINE, Eric HSU, Ghania CHIKH, Anthony CHEUNG
  • DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO
    Publication number: 20180344875
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo
    Patent number: 10046066
    Abstract: Provided herein is chitosan-derivative nanoparticle comprising chitosan functionalized with a cationic amino acid and a hydrophilic polyol; and methods of making and using same, e.g., for gene delivery in vivo.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 14, 2018
    Inventors: Jun Gao, Eric Hsu, Anthony Cheung
  • HIGH CONCENTRATION CHITOSAN-NUCLEIC ACID POLYPLEX COMPOSITIONS
    Publication number: 20180215839
    Abstract: The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provides are methods for altering the diameter of chitosan-nucleic acid polyplexes.
    Type: Application
    Filed: December 20, 2017
    Publication date: August 2, 2018
    Inventors: Eric HSU, Carlos Fleet, Anthony CHEUNG, Jun GAO
  • Dually Derivatized Chitosan Nanoparticles and Methods of Making and Using the Same for Gene Transfer In Vivo
    Publication number: 20180008720
    Abstract: Provided herein is chitosan dually derivatized with arginine and gluconic acid; and methods of making and using the same, e.g., for gene delivery in vivo.
    Type: Application
    Filed: April 17, 2017
    Publication date: January 11, 2018
    Inventors: Jun GAO, Eric HSU, Anthony CHEUNG
  • Display screen or portion thereof with animated graphical user interface
    Patent number: D847198
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: April 30, 2019
    Assignee: PELMOREX CORP.
    Inventors: James Lin Taylor, Matthew Mejaski, Anthony Cheung, Derek Woollam, John A. Gallant, Carrie Lysenko, Ranjita Ghosh